This product is not heat treated during our production process. However, the starting material we receive for this product is heat treated before it reaches us.
126654
Albumin, Human Serum, Non-denatured
Synonym(s):
Albumin, Human Serum, Non-denatured
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About This Item
Assay:
≥95% (SDS-PAGE)
Form:
lyophilized solid (Salt-free)
Technique(s):
protein quantification: suitable
Pricing and availability is not currently available.
description
Merck USA index - 14, 8468
Quality Segment
assay
≥95% (SDS-PAGE)
form
lyophilized solid (Salt-free)
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
technique(s)
protein quantification: suitable
pI
4.7
solubility
water: 20 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
FC(F)(F)C(F)(F)C(F)(F)F
InChI
1S/C3F8/c4-1(5,2(6,7)8)3(9,10)11
InChI key
QYSGYZVSCZSLHT-UHFFFAOYSA-N
General description
Human serum albumin (HSA) is the most abundant protein present in the plasma. It is a monomeric multi-domain macromolecule comprising three homologous domains, numbered I, II, and III. Each domain consists of subdomains A and B with common structural motifs. The HSA gene is mapped to the human chromosome 4q13.3.
High purity plasma protein prepared under non-denaturing conditions.
Application
Albumin, human serum, non-denatured has been used:
- to determine the contribution of albumin protein complexes to esterase activity in saliva,
- in tris buffer for monomer degradation studies and in protein adhesion assay
- to study the effect of Cu2+ and Zn2+ ions on human serum albumin interaction with plasma unsaturated fatty acids
Biochem/physiol Actions
Human serum albumin (HSA) functions as a carrier for fatty acids, steroids, and thyroid hormones. It is used as a supplement in cell culture medium to produce vaccines and pharmaceuticals. HSA is a potential biomarker for various diseases, like cancer, rheumatoid arthritis, ischemia, and post-menopausal obesity. It is also used to treat surgical blood loss, trauma, hemorrhage, and cardiopulmonary bypass. HSA is implicated in biological applications such as implantable biomaterials, surgical adhesives and sealants, and bio chromatography.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Other Notes
Travis, J., and Pannell, R. 1973. Clin. Chem. Acta49, 49.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Toxicity: Standard Handling (A)
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This Item | |||
|---|---|---|---|
| description - | description lyophilized powder, essentially fatty acid free | description lyophilized powder, Fatty acid free, Globulin free, ≥99% (agarose gel electrophoresis) | description lyophilized powder, essentially globulin free, ≥99% (agarose gel electrophoresis) |
| technique(s) protein quantification: suitable | technique(s) western blot: suitable, ELISA: suitable, tissue culture: suitable | technique(s) ELISA: suitable, tissue culture: suitable, western blot: suitable | technique(s) ELISA: suitable, western blot: suitable, tissue culture: suitable |
| assay ≥95% (SDS-PAGE) | assay ≥96% (agarose gel electrophoresis) | assay ≥99% (agarose gel electrophoresis) | assay ≥99% (agarose gel electrophoresis) |
| Quality Level 100 | Quality Level 300 | Quality Level 200 | Quality Level 200 |
| form lyophilized solid (Salt-free) | form lyophilized powder | form lyophilized powder | form lyophilized powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| solubility water: 20 mg/mL | solubility H2O: soluble 50 mg/mL, clear to slightly hazy | solubility H2O: soluble 50 mg/mL | solubility H2O: soluble 20 mg/mL |
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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