E51406

1-Ethynyl-1-cyclohexanol

≥99%

• Synonym(s): (1-Hydroxycyclohexyl)acetylene, (1-Hydroxycyclohexyl)ethyne, 1-Ethynyl-1-hydroxycyclohexane, 1-Ethynylcyclohexanal, 1-Ethynylcyclohexanol, 1-Hydroxy-1-ethynylcyclohexane, Ethynylcyclohexanol
• Linear Formula: HC≡CC₆H₁₀OH
• CAS Number: 78-27-3
• Molecular Weight: 124.18
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24894607
• EC Number: 201-100-9
• Beilstein/REAXYS Number: 471404
• MDL number: MFCD00003858
• Assay: ≥99%

Properties

• vapor pressure: <1 mmHg ( 20 °C)
• Quality Segment: 200
• assay: ≥99%
• bp: 180 °C (lit.)
• mp: 30-33 °C (lit.)
• density: 0.967 g/mL at 25 °C (lit.)
• SMILES string: OC1(CCCCC1)C#C
• InChI: 1S/C8H12O/c1-2-8(9)6-4-3-5-7-8/h1,9H,3-7H2
• InChI key: QYLFHLNFIHBCPR-UHFFFAOYSA-N

Description

Application

1-Ethynyl-1-cyclohexanol (ECHO) can undergo acetylation in the presence of a catalytic amount of ruthenium chloride at room temperature. It can be used to synthesize novel organotellurium(IV) compounds with potent inhibitory activity towards Cathepsin B. The polymerization of ECHO by transition metal catalysts leads to the formation of poly(ECHO). It can also react with transition metal hydride complexes to form vinyl derivatives by inserting into the M-H bonds.

Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H302,H311,H315,H319
• pcodes: P264 - P270 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 1
• flash_point_f: 163.4 °F - closed cup
• flash_point_c: 73 °C - closed cup
• ppe: dust mask type N95 (US), Eyeshields, Faceshields, Gloves