D186252

N,N-Dimethylsulfamoyl chloride

99%

• Synonym(s): Dimethylamidosulfonyl chloride, Dimethylaminosulfonyl chloride, Dimethylsulphamoyl chloride, N,N-Dimethylamidosulfonyl chloride, N,N-Dimethylaminosulfonyl chloride, N,N-Dimethylsulfamoyl chloride, N,N-Dimethylsulfamyl chloride
• Linear Formula: (CH₃)₂NSO₂Cl
• CAS Number: 13360-57-1
• Molecular Weight: 143.59
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24893558
• EC Number: 236-412-4
• Beilstein/REAXYS Number: 741979
• MDL number: MFCD00007425
• Assay: 99%
• Form: liquid

Properties

• Quality Segment: 200
• assay: 99%
• form: liquid
• refractive index: n20/D 1.452 (lit.)
• bp: 114 °C/75 mmHg (lit.)
• density: 1.337 g/mL at 25 °C (lit.)
• SMILES string: CN(C)S(Cl)(=O)=O
• InChI: 1S/C2H6ClNO2S/c1-4(2)7(3,5)6/h1-2H3
• InChI key: JFCHSQDLLFJHOA-UHFFFAOYSA-N

Description

Application

Applications of N,N -dimethylsulfamoyl chloride are:

• It is widely used in the synthesis of a medicinally important class of compounds, sulfonamides.
• It is used in the synthesis of aminotetralin derived sulfamides as anticancer agents and acetylcholinesterase inhibitors.
• It can also be used in the esterification/amidation between carboxylic acids and equimolar amounts of alcohols/amines, as in the synthesis of coumaperine.

Safety Information

• pictograms: GHS06,GHS08,GHS05
• signalword: Danger
• hcodes: H302 + H312,H314,H330,H350
• pcodes: P202 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 2 Inhalation - Acute Tox. 4 Dermal - Acute Tox. 4 Oral - Carc. 1B - Eye Dam. 1 - Skin Corr. 1B
• Storage Class: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk: WGK 3
• flash_point_f: 149.0 °F - closed cup
• flash_point_c: 65 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter