A16807

3-Acetylindole

98%

• Synonym(s): 3-Indolyl methyl ketone, NSC 47180, NSC 58084
• Empirical Formula (Hill Notation): C₁₀H₉NO
• CAS Number: 703-80-0
• Molecular Weight: 159.18
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24890476
• EC Number: 211-875-5
• Beilstein/REAXYS Number: 122579
• MDL number: MFCD00005626
• Assay: 98%
• Form: crystals

Properties

• Quality Segment: 100
• assay: 98%
• form: crystals
• mp: 188-192 °C (lit.)
• SMILES string: CC(=O)c1c[nH]c2ccccc12
• InChI: 1S/C10H9NO/c1-7(12)9-6-11-10-5-3-2-4-8(9)10/h2-6,11H,1H3
• InChI key: VUIMBZIZZFSQEE-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:

• Indole derivatives as antitumor agents
• Endothelin-1 antagonists
• Oncrasin-1 derivatives as inhibitors of the C-terminal domain of RNA polymerase II with antitumor activities
• Inhibitors of hepatitis C NS3/4A serine protease
• Antibacterial agens against MDR Staphylococcus aureus strains
• Antimalarial agents
• Anti-bovine viral diarrhea virus (BVDV) agents
• HIV-1 integrase inhibitors
• Inhibitors of NF-κB transcription regulation related to TNF-α cytokine release

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)