765341
Gold nanoparticles
20 nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H2O
Synonym(s):
Gold nanoparticles NH2 functionalized, Au NP NH2, Gold Colloid
About This Item
Recommended Products
material
PEG 5000
Quality Level
form
dispersion in H2O
nanoparticles
packaging
poly bottle of 1 mL
OD
50
diameter
20 nm
pH
6.0-8.0 (25 °C)
solubility
water: miscible
density
1.00 g/cm3
λmax
520 nm
functional group
amine
storage temp.
2-8°C
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General description
Application
- Since they adhere to cell membranes, AuNPs are used in cellular and intracellular targeting in targeted drug delivery applications and may also be used in biodistribution studies
- AuNPs may also be used in photothermal therapy and radiotherapy.
- Proposed applications of gold nanoparticles are as:drug delivery agents for cancer therapy, coatings, plastics, nanowire, nanofiber, textiles, catalyst applications.
- They may also be used in carrying siRNA which acts against human prostate carcinoma cells by inhibiting a specific cancer gene.
Features and Benefits
- The negatively charged siRNA-PEG complex, attached to positively charged GNPs, is easily cleavable in reductive cytosolic environment thus enabling the release of siRNA into cytosol.
- The PEG coating decreases the cytotoxicity and increases effciciency of GNPs. PEG increases the stability of the nanoparticles and prevents agglomeration.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 2
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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