56210

3-Hydroxypiperidine

≥98.0% (NT)

• Synonym(s): 3-Piperidinol
• Empirical Formula (Hill Notation): C₅H₁₁NO
• CAS Number: 6859-99-0
• Molecular Weight: 101.15
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 57651571
• EC Number: 229-957-4
• Beilstein/REAXYS Number: 102696
• MDL number: MFCD00014591
• Assay: ≥98.0% (NT)
• Form: solid

Properties

• Quality Segment: 200
• assay: ≥98.0% (NT)
• form: solid
• mp: 57-61 °C
• solubility: H₂O: 1 g/mL, clear
• functional group: hydroxyl
• storage temp.: 2-8°C
• SMILES string: OC1CCCNC1
• InChI: 1S/C5H11NO/c7-5-2-1-3-6-4-5/h5-7H,1-4H2
• InChI key: BIWOSRSKDCZIFM-UHFFFAOYSA-N

Description

General description

3-Hydroxypiperidine can be obtained from the reduction of 3-hydroxypyridine.

Application

Reactant for:
Synthesis of unsymmetrical ureas
Synthesis of piperidine nucleoside analogs
Fluorination reactions
Synthesis of substituted pyridines

3-Hydroxypiperidine may be used to synthesize the following:

• 2-pyrrolidinone via oxidation with iodosylbenzene
• 1-[2,8-bis(trifluoromethyl)quinolin-4-yl]piperidin-3-ol via reaction with 4-bromoquinoline

Safety Information

• pictograms: GHS05
• signalword: Danger
• hcodes: H315,H318
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P362 + P364
• Hazard Classifications: Eye Dam. 1 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges