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403245

Sigma-Aldrich

(3-Carboxypropyl)trimethylammonium chloride

technical grade

Synonym(s):

γ-Butyrobetaine hydrochloride, Deoxycarnitine hydrochloride

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About This Item

Linear Formula:
C7H16NO2Cl
CAS Number:
Molecular Weight:
181.66
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

grade

technical grade

mp

220 °C (dec.) (lit.)

SMILES string

[Cl-].C[N+](C)(C)CCCC(O)=O

InChI

1S/C7H15NO2.ClH/c1-8(2,3)6-4-5-7(9)10;/h4-6H2,1-3H3;1H

InChI key

GNRKTORAJTTYIW-UHFFFAOYSA-N

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Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Carnitine synthesis in scorbutic guinea pigs.
Nutrition reviews, 43(6), 185-187 (1985-06-01)
Lisa Adamiak et al.
ACS nano, 11(10), 9877-9888 (2017-10-04)
Cellular uptake by macrophages and ensuing clearance by the mononuclear phagocyte system stands as a significant biological barrier for nanoparticle therapeutics. While there is a growing body of work investigating the design principles essential for imparting nanomaterials with long-circulating characteristics
W J Thoma et al.
Biochimica et biophysica acta, 797(1), 136-139 (1984-01-24)
The effect of ascorbate deficiency on carnitine biosynthesis was investigated in young male guinea pigs. Liver and skeletal muscle carnitine levels were reduced in scorbutic animals. Heart and kidney concentrations remained unchanged. 14C-labeled 4-N-trimethylaminobutyrate was administered to control, pair-fed and
L M Henderson et al.
Federation proceedings, 41(12), 2843-2847 (1982-10-01)
The biosynthesis of carnitine proceeds from trimethyllysine (TML) by beta-hydroxylation by a liver or kidney mitochondrial enzyme, which requires oxygen, alpha-ketoglutarate, ferrous iron, and ascorbate. This dioxygenase is rapidly inactivated by preincubation with Fe2+, but not Fe3+. The evidence suggests
Frédéric M Vaz et al.
The Biochemical journal, 361(Pt 3), 417-429 (2002-01-23)
Carnitine is indispensable for energy metabolism, since it enables activated fatty acids to enter the mitochondria, where they are broken down via beta-oxidation. Carnitine is probably present in all animal species, and in numerous micro-organisms and plants. In mammals, carnitine

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