39205

Dimethylaminomethyl-polystyrene

200-400 mesh particle size, extent of labeling: 3-4 mmol/g base loading, matrix crosslinked with 2% DVB

• Synonym(s): Benzyldimethylamine polymer-bound, Copolymer of styrene and divinylbenzene, dimethylaminomethylated, Polystyrene crosslinked with divinylbenzene, dimethylaminomethylated
• Linear Formula: CH₂N(CH₃)₂ - [CH₂CH(C₆H₅5)]_n
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00144140

Properties

• reaction suitability: reaction type: solution phase peptide synthesis, reactivity: proton reactive
• extent of labeling: 3-4 mmol/g base loading
• impurities: ≤0.5 mmol/g Cl^- (resin)
• matrix: crosslinked with 2% DVB
• particle size: 200-400 mesh
• SMILES string: [X]C(CC(CC(C[X])c3ccc(cc3)CN(C)C)c2ccc(cc2)CN(C)C)c1ccc(cc1)CN(C)C

Description

General description

Dimethylaminomethyl-polystyrene, also known as benzyldimethylamine, is a polystyrene-supported resin crosslinked with divinylbenzene that is commonly used in solution phase peptide synthesis.

Application

Dimethylaminomethyl-polystyrene is used as a resin to synthesize hydrophobic dipeptides such as bis-phenylalanines that can be used in the study of peptide and protein aggregation. Additionally, it can also be utilized for neutralizing acidic solution in a reaction mixture due to its proton reactive nature.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)