391999

5-Methoxy-2-nitrobenzoic acid

97%

• Linear Formula: CH₃OC₆H₃(NO₂)CO₂H
• CAS Number: 1882-69-5
• Molecular Weight: 197.14
• NACRES: NA.22
• PubChem Substance ID: 24864416
• UNSPSC Code: 12352100
• MDL number: MFCD00151836
• Assay: 97%

Properties

• Quality Segment: 100
• assay: 97%
• mp: 125-130 °C (lit.)
• functional group: carboxylic acid, nitro
• SMILES string: COc1ccc(c(c1)C(O)=O)[N+]([O-])=O
• InChI: 1S/C8H7NO5/c1-14-5-2-3-7(9(12)13)6(4-5)8(10)11/h2-4H,1H3,(H,10,11)
• InChI key: URADKXVAIGMTEG-UHFFFAOYSA-N

Description

General description

5-Methoxy-2-nitrobenzoic acid is a substituted 2-nitrobenzoic acid. It has been reported to be one of the microbial degradation metabolite of cypermethrin, a synthetic pyrethroid pesticide.

Application

5-Methoxy-2-nitrobenzoic acid may be used as starting material in the synthesis of the following:

• dictyoquinazol A, a neuroprotective compound
• 5-methoxyantranilic acid by catalytic reduction
• pyrrolobenzodiazepines

5-Methoxy-2-nitrobenzoic acid may be used in the synthesis of the following N-phenylethyl-2-nitrobenzamides:

• N-phenylethyl-5-methoxy-2-nitrobenzamide
• N-(4-methoxyphenylethyl)-5-methoxy-2-nitrobenzamide
• N-(3,4-dimethoxyphenylethyl)-5-methoxy-2-nitrobenzamide
• N-(phenethyl)-5-chloro-2-nitrobenzamide
• N-(3,4-dimethoxyphenethyl)-5-chloro-2-nitrobenzamide

Safety Information

• Storage Class: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable
• PPE (personal protective equipment): Eyeshields, Gloves, type N95 (US)