262102

5,6-Dihydro-2H-pyran-2-one

technical grade, 90%

• Empirical Formula (Hill Notation): C₅H₆O₂
• CAS Number: 3393-45-1
• Molecular Weight: 98.10
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24855858
• MDL number: MFCD00010439
• Beilstein/REAXYS Number: 1610
• Assay: 90%
• Form: liquid

Properties

• grade: technical grade
• Quality Segment: 100
• assay: 90%
• form: liquid
• refractive index: n20/D 1.483 (lit.)
• bp: 103 °C/10 mmHg (lit.)
• density: 1.139 g/mL at 25 °C (lit.)
• functional group: ester
• storage temp.: 2-8°C
• SMILES string: O=C1OCCC=C1
• InChI: 1S/C5H6O2/c6-5-3-1-2-4-7-5/h1,3H,2,4H2
• InChI key: QBDAFARLDLCWAT-UHFFFAOYSA-N

Description

General description

Enantioselective conjugate addition of Grignard reagents to 5,6-dihydro-2H-pyran-2-one catalyzed by a chiral phosphine-copper iodide catalyst has been reported.

Application

5,6-Dihydro-2H-pyran-2-one has been used in the preparation of:

• (1aR,5aR,5bS,6S,7S)-6,7-di-tert-butoxy-5-oxo-pyrrolidino[1,2-b]isoxazolidino[4,5-c]tetrahydropyran
• 4-(phenyl)tetrahydro-2H-pyran-2-one

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk: WGK 3
• flash_point_f: 114.8 °F - closed cup
• flash_point_c: 46 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter