259160

1,4,8,11-Tetraazacyclotetradecane

98% (GC)

• Synonym(s): Cyclam
• Empirical Formula (Hill Notation): C₁₀H₂₄N₄
• CAS Number: 295-37-4
• Molecular Weight: 200.32
• UNSPSC Code: 12352005
• NACRES: NA.22
• PubChem Substance ID: 24855689
• EC Number: 206-039-1
• Beilstein/REAXYS Number: 111811
• MDL number: MFCD00005105

Properties

• assay: 98% (GC)
• mp: 184-186 °C (lit.)
• SMILES string: C1CNCCNCCCNCCNC1
• InChI: 1S/C10H24N4/c1-3-11-7-9-13-5-2-6-14-10-8-12-4-1/h11-14H,1-10H2
• InChI key: MDAXKAUIABOHTD-UHFFFAOYSA-N

Description

General description

1,4,8,11-Tetraazacyclotetradecane is an azamacrocycle that forms more stable metal complexes as compared to open chain ligands.

Application

1,4,8,11-Tetraazacyclotetradecane (cyclam) can be used as a ligand in the synthesis of:

• Cyanide-bridged Fe^III-Cu^II complexes.
• Zinc fenamate complexes [Zn(cyclam)(fen)₂] possessing antimicrobial properties, fen = fenamic acid.
• Zn(II) complexes with flufenamic acid (flu), [Zn(cyclam)(flu)₂].
• Polyoxometalate-metal organic extended framework, for example [{Cu(cyclam)}₃(W₇O₂₄)].15.5.H₂O.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319
• pcodes: P264 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313 - P337 + P313
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves