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Merck

15420

Boc-Gly-OH

≥99.0% (T), for peptide synthesis

Synonym(s):

N-(tert-Butoxycarbonyl)glycine, Boc-glycine

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About This Item

Linear Formula:
(CH3)3COCONHCH2COOH
CAS Number:
Molecular Weight:
175.18
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352209
EC Number:
224-864-5
MDL number:
Beilstein/REAXYS Number:
1101514
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Product Name

Boc-Gly-OH, ≥99.0% (T)

Quality Segment

assay

≥99.0% (T)

form

powder or crystals

reaction suitability

reaction type: Boc solid-phase peptide synthesis

ign. residue

≤0.05%

mp

86-89 °C

application(s)

peptide synthesis

SMILES string

CC(C)(C)OC(=O)NCC(O)=O

InChI

1S/C7H13NO4/c1-7(2,3)12-6(11)8-4-5(9)10/h4H2,1-3H3,(H,8,11)(H,9,10)

InChI key

VRPJIFMKZZEXLR-UHFFFAOYSA-N

Application

Boc-Gly-OH can be used:
  • For the esterification reaction to synthesize N-Boc amino acid esters for peptide chemistry.
  • For the synthesis of tripeptide H-Gly-Pro-Glu-OH, analogs of neuroprotective drugs.
  • As a promoter for the allylation of hydrazones and isatin.



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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Faceshields, Gloves



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