103284

2-Methoxy-5-methylaniline

99%

• Synonym(s): 5-Methyl-o-anisidine, 6-Methoxy-m-toluidine, p-Cresidine
• Linear Formula: CH₃OC₆H₃(CH₃)NH₂
• CAS Number: 120-71-8
• Molecular Weight: 137.18
• UNSPSC Code: 12352100
• NACRES: NA.22
• PubChem Substance ID: 24846603
• EC Number: 204-419-1
• Beilstein/REAXYS Number: 637071
• MDL number: MFCD00007815
• Assay: 99%
• Form: solid

Properties

• vapor density: 4.7 (vs air)
• Quality Segment: 200
• assay: 99%
• form: solid
• bp: 235 °C (lit.)
• mp: 50-52 °C (lit.)
• SMILES string: COc1ccc(C)cc1N
• InChI: 1S/C8H11NO/c1-6-3-4-8(10-2)7(9)5-6/h3-5H,9H2,1-2H3
• InChI key: WXWCDTXEKCVRRO-UHFFFAOYSA-N

Description

General description

2-Methoxy-5-methylaniline is an aromatic amine present as contaminants in commercial hair dye samples.

Application

2-Methoxy-5-methylaniline was used in the synthesis of 4-(4-Amino-5-methoxy-2-methylphenylazo)-5-hydroxy-naphthalene-2,7-disulfonic acid. 2-Methoxy-5-methylaniline was used to analyse the application of polymeric ionic liquids as selective solid-phase microextraction sorbent coatings for the analysis of genotoxic impurities and structurally alerting compounds such as alkyl halides and aromatics. 2-Methoxy-5-methylaniline was used in a study to develop a sensitive analytical method for the determination of aromatic amines found in commercial hair dyes using high liquid chromatography coupled to an electrochemical detector by using the ionic liquid 1-butyl-3-methylimidazolium bis(trifluoromethanesulfonyl)imide in the mobile phase.

Safety Information

• pictograms: GHS08,GHS07
• signalword: Danger
• hcodes: H302,H319,H350
• pcodes: P201 - P301 + P312 + P330 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Carc. 1B - Eye Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: 230.0 °F - closed cup
• flash_point_c: 110 °C - closed cup
• ppe: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges