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A1509

Sigma-Aldrich

Acetyl-DL-carnitine hydrochloride

>98% (TLC)

Synonym(s):

(±)-3-Acetoxy-4-(trimethylammonio)butyrate hydrochloride

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About This Item

Empirical Formula (Hill Notation):
C9H17NO4 · HCl
CAS Number:
2504-11-2
Molecular Weight:
239.70
EC Number:
219-709-3
MDL number:
MFCD00080826
UNSPSC Code:
12352209
PubChem Substance ID:
24890552
NACRES:
NA.26

product name

Acetyl-DL-carnitine hydrochloride,

Assay

>98% (TLC)

Quality Level

200

form

powder

color

white

storage temp.

−20°C

SMILES string

Cl.CC(=O)OC(CC(O)=O)C[N](C)(C)C

InChI

1S/C9H18NO4.ClH/c1-7(11)14-8(5-9(12)13)6-10(2,3)4;/h8H,5-6H2,1-4H3,(H,12,13);1H

InChI key

KEOLEGXENCLAMX-UHFFFAOYSA-N

Biochem/physiol Actions

Weak cholinergic receptor agonist; intermediate in lipid metabolism.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

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J M Mauro et al.
The Biochemical journal, 237(2), 533-540 (1986-07-15)
A photolabile reagent, p-azidophenacyl-DL-thiocarnitine, was synthesized and tested as a photoaffinity label for carnitine acetyltransferase (EC 2.3.1.7) from pigeon breast. p-Azidophenacyl-DL-thiocarnitine is an active-site-directed reagent for this acetyltransferase, since it is a competitive inhibitor (Ki 10 microM) versus carnitine. U.v.
A S Alhomida et al.
Biochimie, 78(3), 204-208 (1996-01-01)
The kinetic properties of carnitine acetyltransferase from the skeletal muscle of the Arabian camel (Camelus dromedarius) were studied. The enzyme showed an optimum pH between 7.2 and 8.2. Reciprocal plots of data obtained by varying one substrate concentration while keeping
P D Prasad et al.
Biochimica et biophysica acta, 1284(1), 109-117 (1996-10-02)
The JAR human placental choriocarcinoma cells were found to transport carnitine into the intracellular space by a Na(+)-dependent process. The transport showed no requirement for anions. The Na+-dependent process was saturable and the apparent Michaelis-Menten constant for carnitine was 12.3
Anna Bogusiewicz et al.
The Journal of nutrition, 145(1), 32-40 (2014-12-21)
A large number of birth defects are related to nutrient deficiencies; concern that biotin deficiency is teratogenic in humans is reasonable. Surprisingly, studies indicate that increased urinary 3-hydroxyisovalerylcarnitine (3HIAc), a previously validated marker of biotin deficiency, is not a valid

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