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54290

Sigma-Aldrich

Hydroxyethyl-cellulose

viscosity 90-160 cP, 5 % in H2O(25 °C)

Synonym(s):

Cellosize® EP-09

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About This Item

CAS Number:
9004-62-0
MDL number:
MFCD00072770
UNSPSC Code:
12352201
NACRES:
NA.25
Pricing and availability is not currently available.

form

powder

Quality Level

100

color

beige

viscosity

90-160 cP, 5 % in H2O(25 °C)

storage temp.

room temp

SMILES string

O1C(C(C(C(C1CO)OC)O)OCCO)OC2C(OC(C(C2O)O)OC4C(OC(C(C4O)O)C)CO)COC3OC(C(C(C3O)O)OC)CO

InChI

1S/C29H52O21/c1-10-15(34)16(35)24(13(8-33)45-10)49-28-20(39)18(37)25(50-29-26(43-5-4-30)21(40)23(42-3)12(7-32)47-29)14(48-28)9-44-27-19(38)17(36)22(41-2)11(6-31)46-27/h10-40H,4-9H2,1-3H3

InChI key

CWSZBVAUYPTXTG-UHFFFAOYSA-N

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General description

Hydroxyethyl cellulose is a gelling and thickening agent derived from cellulose and is widely used in cosmetics, cleaning solutions and other household products. It is used with hydrophobic drugs in capsule formulations, to improve the drugs dissolution in the gastrointestinal fluids. This process is known as hydrophilization.

Application

Hydroxyethylcellulose is used as a gelling and thickening agent in the development of biostructures for the delivery of hydrophobic drugs. Hydroxyethylcellulose is used in the development of polymer networks and block copolymers useful in separation technology such as capillary electrophoresis and in biofilms and coatings. It is also used for encapsulation of cells in chitosan/glycerophosphate/hydroxyethyl cellulose (chitosan-GP/HEC) gels.[1]

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Network-forming polymer in capillary electrophoresis of DNA restriction fragments[2]

Legal Information

CELLOSIZE is a registered trademark of The Dow Chemical Company or an affiliated company of Dow

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
MKCX1532
MKCS9500
MKCS6944
MKCT5459
MKCD0421

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M H Kleemiss et al.
Electrophoresis, 14(5-6), 515-522 (1993-05-01)
Separation of DNA restriction fragments in dilute buffer solutions of network forming polymers such as linear polyacrylamide (PAA), hydroxyethyl cellulose (HEC) and polyvinylalcohol (PVA) in phosphate buffer were investigated. PVA in buffers already became inhomogeneous after a few separations with
Peter Roughley et al.
Biomaterials, 27(3), 388-396 (2005-08-30)
The suitability of chitosan-based hydrogels as scaffolds for the encapsulation of intervertebral disc (IVD) cells and the accumulation of a functional extracellular matrix mimicking that of the nucleus pulposus (NP) was investigated. The specific hypothesis under study was that the
A Semalty et al.
Indian journal of pharmaceutical sciences, 72(5), 571-575 (2011-06-23)
Enalapril maleate is used in the treatment of hypertension and angina pectoris. It shows low bioavailability due to high hepatic first pass metabolism. Hence the present work was undertaken to formulate mucoadhesive buccal films of enalapril maleate with an objective
Fuhu Cao et al.
Electrophoresis, 32(10), 1148-1155 (2011-04-19)
In this work, a novel graft copolymer, hydroxyethylcellulose-graft-poly(2-(dimethylamino)ethyl methacrylate) (HEC-g-PDMAEMA), used as physical coatings of the bare fused-silica capillaries, was synthesized by using ceric ammonium nitrate initiator in aqueous nitric acid solution. EOF measurement results showed that the synthesized HEC-g-PDMAEMA
Temperature-responsive self-assembly of charged and unchargedhydroxyethylcellulose-graft-poly(N-isopropylacrylamide) copolymer in aqueous solution.
Phan HT, Zhu K, Kj?niksen AL, Nystrom B.
Coll. Polymer Sci., 289, 993-1003 (2011)
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Questions

1–3 of 3 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  3. Hello. What is the molecular weight and viscosity of hydroxyethyl cellulose 5429 and hydroxyethyl cellulose 8.22068?

    1 answer

    1. The molecular weight is undetermined. The viscosity is 80-125 cP.

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