D0501
4-Deoxypyridoxine hydrochloride
analytical standard
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About This Item
Empirical Formula (Hill Notation):
C8H11NO2 · HCl
CAS Number:
Molecular Weight:
189.64
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Recommended Products
biological source
synthetic (organic)
Quality Level
grade
analytical standard
Assay
≥98%
technique(s)
HPLC: suitable
gas chromatography (GC): suitable
color
white to yellow
mp
263-265 °C
application(s)
forensics and toxicology
veterinary
vitamins, nutraceuticals, and natural products
format
neat
storage temp.
−20°C
SMILES string
Cl.Cc1ncc(CO)c(C)c1O
InChI
1S/C8H11NO2.ClH/c1-5-7(4-10)3-9-6(2)8(5)11;/h3,10-11H,4H2,1-2H3;1H
InChI key
QZKKOQQIVLXUEI-UHFFFAOYSA-N
General description
4-Deoxypyridoxine hydrochloride is a strong antagonist of vitamin B6.
Application
4-Deoxypyridoxine hydrochloride analytical standard can be used as follows:
- Development of a reversed-phase high-performance liquid chromatographic (RP-HPLC) method combined with mass spectrometric (MS) detection for the impurity analysis of metadoxine drug
- As an internal standard in the ultra- and high- performance liquid chromatographic analysis of pyridoxine in multivitamin tablet samples coupled with UV, mass spectrometric, and fluorescence detector
Other Notes
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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Customers Also Viewed
M Lorenzato et al.
Methods and findings in experimental and clinical pharmacology, 9(10), 649-656 (1987-10-01)
The study was performed with isolated perfused isovolumic rat hearts. After a 40 min stabilization period, the effect of 4-deoxypyridoxine (DOP) 10(-5) M was studied with 3 Glc concentrations: 0, 3.3 and 11 mM. DOP was perfused during a 20
C I Levene et al.
The International journal of biochemistry, 20(12), 1451-1456 (1988-01-01)
1. Treatment of chick embryos with two lathyrogens lowered lysyl oxidase and increased collagen extractability. 2. Subsequent treatment with pyridoxal restored both parameters towards normal, whereas PQQ treatment was less effective. 3. These results suggest the requirement of a pyridoxal
R A Campbell et al.
Life sciences, 48(3), 225-235 (1991-01-01)
DL-alpha-difluoromethylornithine (DFMO), 4-deoxypyridoxine (4-DOP), and methylglyoxal bis (guanylhydrazone) (MGBG) were tested as inhibitors of acute skin graft rejection. Proximal full thickness tail skins were exchanged between C57BL/6 and Balb/C mice. Distal autografts were placed to monitor healing. Inhibitors were given
The effect of pyridoxine on the number of lymphocytes in the blood of rats fed caramel colour (III).
E J Sinkeldam et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 26(3), 195-203 (1988-03-01)
The effect of vitamin E, folic acid, pyridoxine (vitamin B6) and choline on the reduction in circulating lymphocytes in the blood of rats fed Caramel Colour (III) also known as ammonia caramel colour (beer type; AC) has been examined. It
A Trakatellis et al.
Postgraduate medical journal, 70 Suppl 1, S89-S92 (1994-01-01)
Measurements of serine hydroxymethyltransferase (SHMT) in resting lymphocyte cultures showed that the level of activity of this enzyme is very low. Under the influence of mitogenic stimuli serine hydroxymethyltransferase activity is induced 5-20-fold. Addition in the cultures of 4-deoxypyridoxine (dB6)
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