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33420

Sigma-Aldrich

1-Naphthol

puriss. p.a., reag. Ph. Eur., ≥99% (GC)

Synonym(s):

α-Naphthol, 1-Hydroxynaphthalene

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About This Item

Linear Formula:
C10H7OH
CAS Number:
Molecular Weight:
144.17
Beilstein:
1817321
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

Agency

USP/NF
reag. Ph. Eur.

Quality Level

vapor density

4.5 (120 °C, vs air)

vapor pressure

1 mmHg ( 94 °C)

grade

puriss. p.a.

Assay

≥99% (GC)

autoignition temp.

1007 °F

expl. lim.

5 %

impurities

≤0.001% heavy metals (as Pb)
≤0.2% naphthaline (GC)
≤0.2% water (Karl Fischer)
≤0.5% 2-naphthol (GC)

ign. residue

≤0.05% (as SO4)

bp

278-280 °C (lit.)

mp

94-96 °C (lit.)
94-97 °C

anion traces

chloride (Cl-): ≤50 mg/kg

cation traces

Fe: ≤10 mg/kg

SMILES string

Oc1cccc2ccccc12

InChI

1S/C10H8O/c11-10-7-3-5-8-4-1-2-6-9(8)10/h1-7,11H

InChI key

KJCVRFUGPWSIIH-UHFFFAOYSA-N

Gene Information

human ... CYP1A2(1544)

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Application


  • A ′conovenomic′ analysis of the milked venom from the mollusk-hunting cone snail Conus textile--the pharmacological importance of post-translational modifications.: This research underscores the critical role of post-translational modifications in the biological activity of peptides derived from cone snail venom, illustrating the potential for developing novel pharmacological agents using peptide synthesis techniques like those involving Fmoc-Asp(OtBu)-OH (Bergeron et al., 2013).

  • Parallel high-throughput accurate mass measurement using a nine-channel multiplexed electrospray liquid chromatography ultraviolet time-of-flight mass spectrometry system.: This paper discusses a breakthrough in mass spectrometry, highlighting a method for high-throughput analysis which could be critical for the characterization of complex peptide products synthesized using Fmoc-Asp(OtBu)-OH (Fang et al., 2003).


Packaging

bottled under inert gas

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 3 - Eye Dam. 1 - Skin Irrit. 2 - Skin Sens. 1A - STOT SE 2 Oral - STOT SE 3

Target Organs

Kidney, Respiratory system

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

257.0 °F - closed cup

Flash Point(C)

125 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Characterization of duloxetine HCL API and its process related impurities
Karagiannidou E, et al.
International Journal of Analytical, Pharmaceutical and Biomedical Sciences, 3(2) (2014)
Accurate hydrogen-bonding energies between 1-naphthol and water, methanol and ammonia.
Burgi T, et al
Chemical Physics Letters, 246(3), 291-299 (1995)
Baoliang Chen et al.
Chemosphere, 76(1), 127-133 (2009-03-14)
Biochars, derived from biomass, are increasingly recognized as an environmental-friendly sorbent to abate organic pollutants. Sorption variations of biochars with their pyrolytic temperatures are evaluated. Nine biochars of orange peels with different pyrolytic temperatures (150-700 degrees C, referred as OP150-OP700)
Xiaogu Wang et al.
Journal of tissue engineering and regenerative medicine, 9(11), 1310-1320 (2013-01-29)
Synthetic octacalcium phosphate (OCP) has been suggested to be a useful biomaterial for the regeneration of hard tissues, including bone. However, it remains unknown whether OCP induces dentine formation by dental pulp. We investigated biomineralization of dental pulp exposed to
Hongbo Zhang et al.
Toxicology in vitro : an international journal published in association with BIBRA, 26(8), 1286-1293 (2012-01-24)
In vitro glucuronidation assays of diclofenac and indomethacin at pH 7.4 are biased by the instability of the glucuronides due to acyl migration. The extent of this acyl migration may be reduced significantly by performing the glucuronidation reaction at pH

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