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P9404

Sigma-Aldrich

Poly-L-lysine hydrochloride

suitable for cell culture, Mol wt >30,000

Synonym(s):

L-Lysine hydrochloride homopolymer

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About This Item

CAS Number:
26124-78-7
MDL number:
MFCD00081870
UNSPSC Code:
12352209
eCl@ss:
32160406
NACRES:
NA.26

product name

Poly-L-lysine hydrochloride, mol wt >30,000

form

powder

mol wt

>30,000

technique(s)

FTIR: suitable
cell culture | mammalian: suitable

color

white to light yellow

storage temp.

−20°C

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Application

Poly-lysine with mol. wt. >70,000 is useful in promoting cell adhesion to solid substrates.

Analysis Note

Molecular weight based on viscosity.

Other Notes

For additional technical information on polyamino acids please visit the Polyamino acid FAQ resource.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Dendritic cell-targeted protein vaccines: a novel approach to induce T cell immunity.
Trumpfheller C, Longhi MP, et al.
J. Int. Med., 271(2), 183-193 (2011)
Jérôme Roy
Brain research, 1689, 21-29 (2018-03-27)
Microglia are the main resident immunological cells of the central nervous system (CNS) that are functionally equivalent to macrophages. However, due to the cellular heterogeneity of the brain, it is technically challenging to obtain highly specific, healthy microglia with the
C M Gardner et al.
Journal of materials science. Materials in medicine, 23(1), 181-193 (2011-12-20)
Calcium alginate/poly-L-lysine beads were coated with either 50% hydrolyzed poly(methyl vinyl ether-alt-maleic anhydride) (PMM(50)), or with poly(vinyl dimethyl azlactone-co-methacrylic acid) (50:50, PMV(50)), to form covalently shell-crosslinked capsules, and compared with analogous capsules coated with sodium alginate. All capsule types were
Highly compacted DNA nanoparticles with low MW PEG coatings: In vitro, ex vivo and in vivo evaluation.
Boylan NJ, Suk JS, Lai SK, et al.
J. Controlled Release, 157(1), 72-79 (2011)
Nicholas J Boylan et al.
Biomaterials, 33(7), 2361-2371 (2011-12-21)
Highly compacted DNA nanoparticles, composed of single molecules of plasmid DNA compacted with block copolymers of polyethylene glycol and poly-L-lysine (PEG-CK(30)), have shown considerable promise in human gene therapy clinical trials in the nares, but may be less capable of
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