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205494

Sigma-Aldrich

Dibutyltin dichloride

96%

Synonym(s):

Dibutyldichlorotin

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About This Item

Linear Formula:
(CH3CH2CH2CH2)2SnCl2
CAS Number:
683-18-1
Molecular Weight:
303.84
Beilstein:
3535484
EC Number:
211-670-0
MDL number:
MFCD00000518
UNSPSC Code:
12352103
PubChem Substance ID:
24852336
NACRES:
NA.22

Quality Level

100

Assay

96%

form

solid

bp

135 °C/10 mmHg (lit.)

mp

37-40 °C (lit.)

SMILES string

CCCC[Sn](Cl)(Cl)CCCC

InChI

1S/2C4H9.2ClH.Sn/c2*1-3-4-2;;;/h2*1,3-4H2,2H3;2*1H;/q;;;;+2/p-2

InChI key

RJGHQTVXGKYATR-UHFFFAOYSA-L

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Application

  • Effects of dibutyltin compounds on PPARγ/RXRα activity: Studies the impact of various dibutyltin compounds, including dibutyltin dichloride, on adipogenesis and inflammation in mammalian cells, emphasizing their effects on the PPARγ/RXRα pathway (Milton et al., 2017).

Signal Word

Danger

Hazard Classifications

Acute Tox. 2 Inhalation - Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Muta. 2 - Repr. 1B - Skin Corr. 1B - Skin Sens. 1 - STOT RE 1 Oral - STOT SE 1 Oral

Target Organs

thymus

Storage Class Code

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sumatriptan is used specifically to relieve headache pain. The possible efficacy of sumatriptan was investigated in 2 models of visceral pain. Pancreatic inflammation was induced by intravenous injection of dibutyltin dichloride. Noninflammatory irritable bowel syndrome was induced by intracolonic instillation
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Because of the vital importance of the proteasome pathway, chemicals affecting proteasome activity could disrupt essential cellular processes. Although the toxicity of organotins to both invertebrates and vertebrates is well known, the essential cellular target of organotins has not been
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