140325

8-Hydroxy-5-nitroquinoline

96%

• Synonym(s): 5-Nitro-8-quinolinol
• Empirical Formula (Hill Notation): C₉H₆N₂O₃
• CAS Number: 4008-48-4
• Molecular Weight: 190.16
• EC Number: 223-662-4
• MDL number: MFCD00006791
• UNSPSC Code: 12352100
• PubChem Substance ID: 24848465
• NACRES: NA.22

Properties

• Assay: 96%
• form: powder
• mp: 181-183 °C (lit.)
• solubility: alcohol: very slightly soluble; diethyl ether: very slightly soluble; hydrochloric acid: freely soluble (hot)
• SMILES string: Oc1ccc([N+]([O-])=O)c2cccnc12
• InChI: 1S/C9H6N2O3/c12-8-4-3-7(11(13)14)6-2-1-5-10-9(6)8/h1-5,12H
• InChI key: RJIWZDNTCBHXAL-UHFFFAOYSA-N

Description

Application

8-Hydroxy-5-nitroquinoline was used in the synthesis of novel CO₂-soluble 8-hydroxyquinoline chelating agents.

Biochem/physiol Actions

8-Hydroxy-5-nitroquinoline is an effective anti-microbial and anti-cancer agent. It is an effective drug for the treatment of urinary tract infections due to gram negative bacilli.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301 + H311 + H331,H315,H319,H335
• Precautionary Statements: P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves