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RAB0824

Sigma-Aldrich

Mouse Olr1 / Oxidized Low-density Lipoprotein Receptor 1 ELISA Kit

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About This Item

UNSPSC Code:
41116158
NACRES:
NA.84

species reactivity

mouse

packaging

kit of 96 wells (12 strips x 8 wells)

technique(s)

ELISA: suitable

assay range

inter-assay cv: <10%
intra-assay cv: <12%

detection method

colorimetric

shipped in

wet ice

storage temp.

−20°C

Gene Information

mouse ... Olr1(108078)

General description

The antibody pair provided in this kit recognizes mouse Oxidized Low-density Lipoprotein Receptor 1.

Application

For research use only. Not for use in diagnostic procedures.
Please refer to the attached General ELISA KIT Procedure (sandwich, competitive & Indirect ELISA)

Biochem/physiol Actions

Oxidized low-density lipoprotein receptor 1 (OLR1), also referred as Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1), acts as a scavenger receptor for oxidized low-density lipoprotein (ox-LDL). It is essential for formation and progression of atherosclerotic plaques. Therefore, mutation in the gene increases the risk of susceptibility to atherosclerotic-related diseases. In addition, genetic variation in the gene leads to myocardial infarction. Serum concentration of OLR1 serves as an efficient biomarker of intracerebral hemorrhage (ICH).

Kit Components Also Available Separately

Product No.
Description
SDS

  • RABTMB3ELISA Colorimetric TMB Reagent (HRP Substrate, Item H)SDS

  • RABSTOP3ELISA Stop Solution (Item I)SDS

  • RABWASH420X Wash Buffer (Item B)SDS

Pictograms

Corrosion

Signal Word

Warning

Hazard Statements

Precautionary Statements

Hazard Classifications

Met. Corr. 1

Storage Class Code

8A - Combustible corrosive hazardous materials

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction
Tatsuguchi M, et al.
Biochemical and Biophysical Research Communications, 303(1), 247-250 (2003)
LOX-1 and atherosclerotic-related diseases.
Jin P and Cong S
Clinica Chimica Acta; International Journal of Clinical Chemistry, 491, 24-29 (2019)
Chiyo Nakashima-Nakasuga et al.
International journal of clinical oncology, 25(7), 1308-1317 (2020-04-12)
Colorectal cancer is the third most common cancer worldwide. If biomarkers can be identified in liquid biopsy, diagnosis and treatment can be optimized even when cancerous tissues are not available. The purpose of this study was to identify proteins from
Lectin-Like Oxidized Low-Density Lipoprotein Receptor-1 Levels as a Biomarker of Acute Intracerebral Hemorrhage
Inoue T, et al.
Journal of Stroke and Cerebrovascular Diseases : The Official Journal of National Stroke Association, 28(2), 490-494 (2019)
Akshay Sood et al.
The Journal of asthma : official journal of the Association for the Care of Asthma, 51(5), 459-466 (2014-01-23)
Adipose tissue produces adiponectin, an anti-inflammatory protein. High systemic total adiponectin is associated with a low risk for incident asthma but the association with lung adiponectin is not known. Our objective was to evaluate the association between sputum total adiponectin

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