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Key Documents

C0128

Sigma-Aldrich

α-Chloralose

Synonym(s):

1,2-O-(2,2,2-Trichloroethylidene)-α-D-glucofuranose, Anhydro-D-glucochloral, Chloralose

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About This Item

Empirical Formula (Hill Notation):
C8H11Cl3O6
CAS Number:
Molecular Weight:
309.53
Beilstein:
85418
EC Number:
MDL number:
UNSPSC Code:
12352201
PubChem Substance ID:
NACRES:
NA.25

form

powder

impurities

≤20% β-anomer

color

white to off-white

solubility

ethanol: 10 mg/mL, clear to slightly hazy, colorless to faintly yellow (or yellow-brown)

SMILES string

OC[C@@H](O)[C@H]1O[C@@H]2O[C@@H](O[C@@H]2[C@H]1O)C(Cl)(Cl)Cl

InChI

1S/C8H11Cl3O6/c9-8(10,11)7-16-5-3(14)4(2(13)1-12)15-6(5)17-7/h2-7,12-14H,1H2/t2-,3+,4-,5-,6-,7-/m1/s1

InChI key

OJYGBLRPYBAHRT-IPQSZEQASA-N

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Application

α-Chloralose has been used as anesthetic in surgical preparations.

Biochem/physiol Actions

α-Chloralose is used as an immobilizing agent. It is mostly used in studies, which involves autonomic reflexes. α-Chloralose is a sedative hypnotic. It has high significance as anesthetic for laboratory animals.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pictograms

Skull and crossbonesEnvironment

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Aquatic Acute 1 - Aquatic Chronic 1 - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Preparation of water-soluble compounds by covalent attachment of solubilizing moieties
The Practice of Medicinal Chemistry, 767-785 (2008)
Vertebrate pest control chemicals and their use in urban and rural environments
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Serotonin in the solitary tract nucleus shortens the laryngeal chemoreflex in anaesthetized neonatal rats
Donnelly WT, et al.
Experimental Physiology, 101(7), 946-961 (2016)
Activation of serotonergic neurons in the medullary caudal raphe shortens the laryngeal chemoreflex in anaesthetized neonatal rats
Donnelly WT, et al.
Experimental Physiology, 102(8), 1007-1018 (2017)
Preanesthesia, anesthesia, analgesia, and euthanasia
Laboratory Animal Medicine, 1135-1200 (2015)

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