53796
(Z-)-4-Bromo-5-(bromomethylene)-2(5H)-furanone
≥97.0% (GC)
Synonym(s):
Furanone C-30
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About This Item
Empirical Formula (Hill Notation):
C5H2Br2O2
CAS Number:
Molecular Weight:
253.88
Beilstein:
120928
MDL number:
UNSPSC Code:
12352106
PubChem Substance ID:
NACRES:
NA.25
Recommended Products
Assay
≥97.0% (GC)
97.0-103.0% (T)
form
solid
storage temp.
−20°C
SMILES string
Br\C=C1/OC(=O)C=C1Br
InChI
1S/C5H2Br2O2/c6-2-4-3(7)1-5(8)9-4/h1-2H/b4-2-
InChI key
DPGLBHQUHFJRJS-RQOWECAXSA-N
Biochem/physiol Actions
The synthetic furanones C30 interfered with the actions of acyl-HSL molecules and inhibited gene expression regulated by quorum-sensing systems in P. aeruginosa.
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Yang Zhao et al.
Bioresource technology, 186, 52-57 (2015-03-25)
The aim of this study was to determine whether acid mine drainage (AMD) production can be decreased by (5Z)-4-bromo-5-(bromomethylene)-2(5H)-furanone (furanone C-30) in the presence of Acidithiobacillus ferrooxidans (A. ferrooxidans). The effects of furanone C-30 on A. ferrooxidans biofilm production were
Jingming Zhao et al.
The Indian journal of medical research, 147(4), 400-406 (2018-07-13)
Pseudomonas aeruginosa is an opportunistic pathogen that can cause nosocomial bloodstream infections in humans. This study was aimed to explore the association of furanone C-30 with biofilm formation, quorum sensing (QS) system and antibiotic resistance in P. aeruginosa. An in
H Wu et al.
The Journal of antimicrobial chemotherapy, 53(6), 1054-1061 (2004-05-01)
Antibiotics are used to treat bacterial infections by killing the bacteria or inhibiting their growth, but resistance to antibiotics can develop readily. The discovery that bacterial quorum-sensing regulates bacterial virulence as well as the formation of biofilms opens up new
Prateeksha et al.
Frontiers in cellular and infection microbiology, 7, 93-93 (2017-04-08)
Honey is an excellent source of polyphenolic compounds that are effective in attenuating quorum sensing (QS), a chemical process of cell-to-cell communication system used by the opportunistic pathogen
Adeline Conceição Rodrigues et al.
Biofouling, 36(9), 1031-1048 (2020-11-15)
Serratia liquefaciens is a spoilage microorganism of relevance in the dairy industry because it is psychrotrophic, able to form biofilm, and produces thermoresistant proteases and lipases. Phenolic compounds and furanones have been studied as inhibitors of biofilm formation. In this
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