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45842

Supelco

Diazinon solution

100 μg/mL in acetonitrile, PESTANAL®, analytical standard

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About This Item

Empirical Formula (Hill Notation):
C12H21N2O3PS
CAS Number:
Molecular Weight:
304.35
Beilstein:
273790
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

concentration

100 μg/mL in acetonitrile

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
environmental

format

single component solution

storage temp.

2-8°C

SMILES string

CCOP(=S)(OCC)Oc1cc(C)nc(n1)C(C)C

InChI

1S/C12H21N2O3PS/c1-6-15-18(19,16-7-2)17-11-8-10(5)13-12(14-11)9(3)4/h8-9H,6-7H2,1-5H3

InChI key

FHIVAFMUCKRCQO-UHFFFAOYSA-N

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General description

Diazinon, belongs to the organophosphorus class of pesticides, extensively used in agriculture. Its mode of action involves the inhibition of cholinesterase in insects and mammals and also brings about non-reversible phosphorylation of esterases in the central nervous system of the organism.

Application

Diazinon may be used as an analytical reference standard for the quantification of the analyte in aqueous samples and biological samples using different chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Pictograms

FlameExclamation mark

Signal Word

Danger

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Eye Irrit. 2 - Flam. Liq. 2

Storage Class Code

3 - Flammable liquids

WGK

WGK 3

Flash Point(F)

35.6 °F - closed cup

Flash Point(C)

2 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Determination of ethoprop, diazinon, disulfoton and fenthion using dynamic hollow fiber-protected liquid-phase microextraction coupled with gas chromatography--mass spectrometry
Chen S-P and Huang D-S
Talanta, 85(3), 669-675 (2006)
Liquid chromatography--tandem mass spectrometry method for the simultaneous quantitative determination of the organophosphorus pesticides dimethoate, fenthion, diazinon and chlorpyrifos in human blood
Salm P, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 877(5-6), 568-574 (2009)
Mahvash Jafari et al.
Toxicology mechanisms and methods, 22(8), 638-647 (2012-08-09)
Diazinon (DZN) is an organophosphate pesticide widely used in agricultural to control insects and in veterinary medicine to control ectoparasites. This study investigated the induction of oxidative stress in the brain, heart, and spleen of Wistar and Norway rats treated
Karen Huen et al.
Environmental research, 117, 8-16 (2012-06-12)
Organophosphate pesticides are widely used and recent studies suggest associations of in utero exposures with adverse birth outcomes and neurodevelopment. Few studies have characterized organophosphate pesticides in human plasma or established how these levels correlate to urinary measurements. We measured
Xiao Zhang et al.
Environmental toxicology and pharmacology, 34(3), 959-968 (2012-09-12)
Pesticide exposure has repeatedly been associated with cancers. However, molecular mechanisms are largely undetermined. In this study, we examined whether exposure to diazinon, a common organophosphate that has been associated with cancers, could induce DNA methylation alterations. We conducted genome-wide

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