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Key Documents

1361009

USP

Levodopa

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

3,4-Dihydroxy-L-phenylalanine, 3-(3,4-Dihydroxyphenyl)-L-alanine, L-3-Hydroxytyrosine, L-DOPA, Levodopa

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About This Item

Linear Formula:
(HO)2C6H3CH2CH(NH2)CO2H
CAS Number:
Molecular Weight:
197.19
Beilstein:
2215169
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24
Pricing and availability is not currently available.

grade

pharmaceutical primary standard

API family

levodopa

manufacturer/tradename

USP

mp

276-278 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

N[C@@H](Cc1ccc(O)c(O)c1)C(O)=O

InChI

1S/C9H11NO4/c10-6(9(13)14)3-5-1-2-7(11)8(12)4-5/h1-2,4,6,11-12H,3,10H2,(H,13,14)/t6-/m0/s1

InChI key

WTDRDQBEARUVNC-LURJTMIESA-N

Gene Information

human ... DRD3(1814)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Levodopa USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Carbidopa and Levodopa Tablets
  • Carbidopa and Levodopa Orally Disintegrating Tablets
  • Carbidopa and Levodopa Extended-Release Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Pictograms

Exclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Certificates of Analysis (COA)

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Carbidopa and Levodopa Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 47(5) (2022)
Levodopa
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 40(1), 2604-2604 (2020)
Carbidopa and Levodopa Orally Disintegrating Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 44(1), 759-759 (2022)
Carbidopa and Levodopa Extended-Release Tablets
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(3), 753-753 (2018)
Lukas L Imbach et al.
Parkinsonism & related disorders, 20(11), 1283-1286 (2014-09-28)
Diagnosis and treatment of tremor are largely based on clinical assessment. Whereas in some patients tremor may respond to dopaminergic treatment, in general l-Dopa response to tremor varies considerably. The aim of this study was to predict l-Dopa response by

Questions

  1. Hi, I hope this message finds you well. We would like to order the Levodopa (1361009 USP), could you please let me know how should we dissolve the reagent and how to store the solution? How long can we store the solution for cell culture use? Thank you!

    1 answer
    1. This product is slightly soluble in water and acidic solutions, and practically insoluble in ethanol. It is unstable in aqueous alkaline solutions. Solutions should be freshly prepared, as the product is rapidly oxidized by air and may darken when exposed to air and light.

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