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47783

Supelco

(±)-α-Tocopherol

analytical standard

Synonym(s):

DL-all-rac-α-Tocopherol, Vitamin E

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About This Item

Empirical Formula (Hill Notation):
C29H50O2
CAS Number:
10191-41-0
Molecular Weight:
430.71
Beilstein:
94012
EC Number:
233-466-0
MDL number:
MFCD00006848
UNSPSC Code:
12164500
PubChem Substance ID:
24871420
E Number:
E307
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

100

form

liquid

CofA

current certificate can be downloaded

feature

standard type fat soluble vitamin

packaging

ampule of 100 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

density

0.950 g/mL at 20 °C (lit.)

application(s)

food and beverages

format

neat

storage temp.

-10 to -25°C

SMILES string

CC(C)CCCC(C)CCCC(C)CCCC1(C)CCc2c(C)c(O)c(C)c(C)c2O1

InChI

1S/C29H50O2/c1-20(2)12-9-13-21(3)14-10-15-22(4)16-11-18-29(8)19-17-26-25(7)27(30)23(5)24(6)28(26)31-29/h20-22,30H,9-19H2,1-8H3

InChI key

GVJHHUAWPYXKBD-UHFFFAOYSA-N

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General description

α-Tocopherol is a form of fat-soluble vitamin E and shows anti-oxidant, anti-inflammatory, anti-cell proliferative, and anti-cancer properties.
This substance is listed on the positive list of the EU regulation 10/2011 for plastics intended to come into contact with food. Find all available reference materials for compounds listed in 10/2011 here

Application

The analytical standard can also be used as follows:

  • Simultaneous determination of vitamin A and all four tocopherol isomers in human serum samples by ultra-high performance liquid chromatography (UHPLC) combined with fluorescence detection following their liquid-liquid extraction (LLE)
  • Multi-residue analysis of vitamin B (B1, B2, B5, and B9), and vitamin E (α-tocopherol, β-tocopherol, α-tocotrienol, and β-tocotrienol) in grass and grain samples of four different wheat varieties by liquid chromatography-electrospray ionization/multistage mass spectrometry (LC-ESI-MS/MS)
  • Separation and estimation of four tocopherols and four tocotrienols in pecan nut cultivar samples using non-aqueous reversed-phase high-performance liquid chromatography (NARP-HPLC) coupled with atmospheric pressure chemical ionization-tandem mass spectrometric (APCI-MS/MS) detection
  • Analysis of different cold pressed oil samples to detect and quantify eight tocol- homologs using a chemometrically-assisted optimized high-performance liquid chromatography (HPLC) with fluorescence detection (FLD) based method
  • Multi-residue determination of tocopherols in aromatic peanut oil (APO) and four refined vegetable oils using high-performance liquid chromatography with UV detection to detect adulteration

Other Notes

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H317

Hazard Classifications

Skin Sens. 1

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

235.4 °F - closed cup

Flash Point(C)

113 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
LRAD1376
LC26915V
LC26583V
LC25784V
LC25615V

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Simultaneous determination of retinol, ?-tocopherol and ?-carotene in serum by isocratic high-performance liquid chromatography
Arnaud.J, et al.
Journal of Chromatography. B, Biomedical Applications, 572(1-2), 103-116 (1991)
Simultaneous determination of plasma retinol, alpha-tocopherol, lycopene, alpha-carotene, and beta-carotene by high-performance liquid chromatography.
Miller WK, et al.
Analytical Biochemistry, 138(2), 340-345 (1984)
Guowei Zheng et al.
Plant diversity, 42(1), 44-51 (2020-03-07)
Understanding the responses of crops to elevated atmospheric carbon dioxide concentrations (E[CO2]) is very important in terms of global food supplies. The present study investigates the effects of CO2 enrichment (to 800 μmol mol-1) on the physiology of soybean plants and the
George Gachumi et al.
Molecules (Basel, Switzerland), 26(5) (2021-04-04)
Phytosterols and tocopherols are commonly used in food and pharmaceutical industries for their health benefits. Current analysis methods rely on conventional liquid chromatography, using an analytical column, which can be tedious and time consuming. However, simple, and fast analytical methods
Sam B Weber et al.
Proceedings. Biological sciences, 279(1731), 1077-1084 (2011-09-23)
The effect of climate warming on the reproductive success of ectothermic animals is currently a subject of major conservation concern. However, for many threatened species, we still know surprisingly little about the extent of naturally occurring adaptive variation in heat-tolerance.
View All Related Papers

Protocols

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® Si

HPLC Analysis of Fat Soluble Vitamins by Normal Phase Chromatography on Ascentis® S

HPLC Analysis of Vitamins, Fat Soluble (A and E), on SUPELCOSIL™ LC-18

Separation of δ-Tocopherol, analytical standard; Retinyl acetate; (+)-γ-Tocopherol; α-Tocopherol, ≥95.5%; Retinol; Vitamin A (acetate), meets USP testing specifications.

Questions

1–4 of 4 Questions  

  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  2. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

      Helpful?

  3. What does Product No. 47783 DL-alpha Tocopherol come packaged in and how should it be stored?

    1 answer

    1. Product No. 47783 comes packaged in a 4ml amber glass vial with a solid Teflon lined cap. should be stored in a freezer.

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  4. What is the Department of Transportation shipping information for this product?

    1 answer

    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

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