SRP6388

LAMP1/CD107a human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in HEK 293 cells
• tag: 6-His tagged (C-terminus)
• Assay: ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: calculated mol wt 39.2 kDa; observed mol wt 60-100 kDa (DTT-reduced. Protein migrates due to different glycosylation. Ala 29 is the predicted N-terminus.)
• packaging: pkg of 10 and 50 μg
• impurities: <1 EU/μg endotoxin (LAL test)
• UniProt accession no.: P11279
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... LAMP1(3916)

Description

General description

Lysosomal-associated membrane protein 1 (LAMP1) is also known as CD107a (Cluster of Differentiation 107a). LAMP1 / CD107a belongs to the LAMP family. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. CD107a has also been shown to be a marker of degranulation on lymphocytes such as CD8+ and NK cells.

Physical form

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution

Centrifuge the vial prior to opening. Reconstitute in sterile PBS, pH 7.4 to a concentration of 50 μg/mL. Do not vortex. This solution can be stored at 2-8°C for up to 1 month. For extended storage, it is recommended to store at -20°C.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable