SRP4505

FABP5 human

recombinant, expressed in E. coli

• Synonym(s): E-FABP, Epidermal-type fatty acid-binding protein, Fatty acid-binding protein 5, Fatty acid-binding protein epidermal, Psoriasis-associated fatty acid-binding protein homolog
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in E. coli
• Assay: ≥98% (SDS-PAGE)
• form: lyophilized
• mol wt: ~16 kDa
• packaging: pkg of 100 μg
• storage condition: avoid repeated freeze/thaw cycles
• impurities: endotoxin, tested
• NCBI accession no.: Q01469
• UniProt accession no.: Q01469
• shipped in: wet ice
• storage temp.: −20°C
• Gene Information: human ... FABP5(2171)

Description

General description

FABPs (fatty acid-binding proteins) are small 14-15kDa intracellular cytosolic proteins. They are needed for the transport of lipids to specific areas in cells.[1] The FABP5 gene is mapped to human chromosome 8q21.[2]

Biochem/physiol Actions

FABP5 (fatty acid-binding protein 5) is involved in the pathogenesis of metabolic diseases. Absence of FABP-4 and -5 in mice protects them against diet-induced obesity, insulin resistance, type 2 diabetes, atherosclerosis and fatty liver disease.[1] FABP5 is also associated with bladder, pancreas, prostate, breast cancers and glioblastoma.[3]

Physical form

Sterile filtered and Lyophilized without additives.

Reconstitution

Centrifuge the vial prior to opening. Avoid freeze-thaw cycles.

Reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable