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SRP0488

Sigma-Aldrich

PLA2G12A human

recombinant, expressed in mammalian cells, ≥80% (SDS-PAGE)

Synonym(s):

GXII, Phospholipase A2 G12, ROSSY

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About This Item

UNSPSC Code:
12352202
NACRES:
NA.32
Pricing and availability is not currently available.

biological source

human

recombinant

expressed in mammalian cells

Assay

≥80% (SDS-PAGE)

form

aqueous solution

mol wt

22 kDa

packaging

pkg of 10 and 20 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

0.14 mg/mL

UniProt accession no.

Q9BZM1

shipped in

dry ice

storage temp.

−20°C

Gene Information

human ... PLA2G12A(81579)

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PLA2G12A human recombinant, expressed in mammalian cells, ≥80% (SDS-PAGE)

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PLA2G12B human recombinant, expressed in mammalian cells, ≥60% (SDS-PAGE)

SRP0489

PLA2G12B human

PARP1 Active human recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE)

SRP0192

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Sphingosine-1-phosphate lyase1 Active human recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE)

SRP0191

Sphingosine-1-phosphate lyase1 Active human

assay

≥80% (SDS-PAGE)

assay

≥60% (SDS-PAGE)

assay

≥80% (SDS-PAGE)

assay

≥70% (SDS-PAGE)

biological source

human

biological source

human

biological source

human

biological source

human

concentration

0.14 mg/mL

concentration

-

concentration

>0.02 mg/mL

concentration

0.19 mg/mL

recombinant

expressed in mammalian cells

recombinant

expressed in mammalian cells

recombinant

expressed in baculovirus infected insect cells

recombinant

expressed in baculovirus infected insect cells

form

aqueous solution

form

aqueous solution

form

aqueous solution

form

aqueous solution

General description

Human PLA2G12A (GenBank Accession No. NM_030821), amino acids 23-189(end) with C-terminal His-tag, MW=22 kDa, expressed in a mammalian cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Physical form

Fomulated in 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 200 mM Imidazole, and 20% Glycerol.

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Danger

Hazard Statements

H315,H319,H360D

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
6009211205

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Marianne Berg et al.
Molecular cancer, 9, 100-100 (2010-05-13)
Estimates suggest that up to 30% of colorectal cancers (CRC) may develop due to an increased genetic risk. The mean age at diagnosis for CRC is about 70 years. Time of disease onset 20 years younger than the mean age

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