SRP0483
CREBBP (1081-1197) His tag human
recombinant, expressed in E. coli, ≥90% (SDS-PAGE)
Synonym(s):
CBP, CREB binding protein, KAT3A, RSTS
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About This Item
UNSPSC Code:
12352200
NACRES:
NA.32
biological source
human
recombinant
expressed in E. coli
Assay
≥90% (SDS-PAGE)
form
aqueous solution
mol wt
14.9 kDa
packaging
pkg of 100 μg
storage condition
avoid repeated freeze/thaw cycles
concentration
1.26 mg/mL
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−70°C
Gene Information
human ... CREBBP(1387)
General description
Human bromodomain CREB binding protein (CREBBP), also known as CBP, RSTS and KAT3A (GenBank Accession No. NM_004380) amino acids 1081- 1197 with N-terminal His-tag, MW=14.9 kDa, expressed in an E. coli expression system.
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
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Wei-Chien Huang et al.
Molecular cell, 26(1), 75-87 (2007-04-17)
CBP plays a central role in coordinating and integrating multiple signaling pathways. Competition between NF-kappaB and p53 for CBP is a crucial determinant of whether a cell proliferates or undergoes apoptosis. However, how the CBP-dependent crosstalk between these two transcription
I Panagopoulos et al.
Human molecular genetics, 10(4), 395-404 (2001-02-07)
The CBP gene at 16p13 fuses to MOZ and MLL as a result of the t(8;16)(p11;p13) in acute (myelo)monocytic leukemias (AML M4/M5) and the t(11;16)(q23;p13) in treatment-related AML, respectively. We show here that a novel t(10;16)(q22;p13) in a childhood AML
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