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SML2525

Tafluprost

≥98% (HPLC)

Synonym(s):

(5Z)-7-[(1R,2R,3R,5S)-2-[(1E)-3,3-Difluoro-4-phenoxy-1-buten-1-yl]-3,5-dihydroxycyclopentyl]-5-heptenoic acid 1-methylethyl ester, 16-phenoxy-15-deoxy-15,15-difluoro-17,18,19,20-tetranorprostaglandin F2α isopropyl ester, AFP-168

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About This Item

Empirical Formula (Hill Notation):
C25H34F2O5
CAS Number:
Molecular Weight:
452.53
UNSPSC Code:
51111800
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
oil
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assay

≥98% (HPLC)

form

oil

optical activity

[α]/D +20 to +25°, c = 1 in chloroform-d

color

colorless to yellow

storage temp.

−20°C

SMILES string

FC(F)(COc2ccccc2)\C=C\C1C(CC(C1C\C=C\CCCC(=O)OC(C)C)O)O

InChI

1S/C25H34F2O5/c1-18(2)32-24(30)13-9-4-3-8-12-20-21(23(29)16-22(20)28)14-15-25(26,27)17-31-19-10-6-5-7-11-19/h3,5-8,10-11,14-15,18,20-23,28-29H,4,9,12-13,16-17H2,1-2H3/b8-3+,15-14+

InChI key

WSNODXPBBALQOF-ZHDUIJGQSA-N

Biochem/physiol Actions

Prostaglandin F2α agonist; Antiglaucoma agent
Taflupost is a prostaglandin F2α agonist that lowers intraocular pressure and is used in the treatment of glaucoma. It has high affinity and selectivity for the fluoroprostaglandin (FP) receptor PGF2α. Tafluprost is believed to reduce the intraocular pressure (IOP) by increasing the outflow of aqueous humor. Tafluprost is a pro-drug. The active metabolite is the free acid.

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This Item
SML21061686003
description

≥98% (HPLC)

description

≥98% (HPLC)

description

United States Pharmacopeia (USP) Reference Standard

assay

≥98% (HPLC)

assay

≥98% (HPLC)

assay

-

form

oil

form

oil

form

-

storage temp.

−20°C

storage temp.

2-8°C

storage temp.

-

color

colorless to yellow

color

colorless to light brown

color

-

optical activity

[α]/D +20 to +25°, c = 1 in chloroform-d

optical activity

-

optical activity

-


Pictograms

Health hazard

Signal Word

Warning

Hazard Codes

Hazard Classifications

Repr. 2

Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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