Unfortunately, the solution stability of this product is not determined.
SML2156
Erlotinib hydrochloride
≥98% (HPLC)
Synonym(s):
774 hydrochloride, CP-358, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride, OSI-744 hydrochloride
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About This Item
Empirical Formula (Hill Notation):
C22H23N3O4 · HCl
CAS Number:
Molecular Weight:
429.90
MDL number:
UNSPSC Code:
12352200
NACRES:
NA.77
Pricing and availability is not currently available.
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Assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 2 mg/mL, clear (warmed)
storage temp.
−20°C
SMILES string
Cl.N(c3cc(ccc3)C#C)c1ncnc2c1cc(c(c2)OCCOC)OCCOC
InChI
1S/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
InChI key
GTTBEUCJPZQMDZ-UHFFFAOYSA-N
General description
Application
Erlotinib hydrochloride has been used to activate mitochondrial fragmentation in a human PANC-1 pancreatic cancer cell line.[2]
Biochem/physiol Actions
EGFR kinase inhibitor; Antineoplastic
Erlotinib hydrochloride is an inhibitor of the receptor tyrosine kinase EGFR (epidermal growth factor receptor). It is used clinically for the treatment of non-small cell lung cancer (NSCLC) and in combination for metastatic pancreatic cancer.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Acute Tox. 4 Oral
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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How long is your erlotinib hydrochloride stable as aliquots dissolved in DMSO or water at -20 degrees? And how long is it stable when added to cell culture medium at 37 degrees at 5% CO2?
1 answer-
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