SAB3501226

Anti-TRBP1 antibody produced in rabbit

affinity isolated antibody

• UNSPSC Code: 12352203
• NACRES: NA.43

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• species reactivity: human, mouse
• concentration: 1 mg/mL
• technique(s): western blot: suitable
• isotype: IgG
• NCBI accession no.: NP_005637
• UniProt accession no.: Q13395
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... TARBP1(6894)

Description

General description

TRBP1 Antibody: The human trans-activation response (TAR) RNA binding protein 1 (TRBP1) was initially identified as a protein that binds to the HIV-1 TAR RNA and activates the long terminal repeat (LTR) expression in the absence and presence of the viral trans-activator Tat. This binding is enhanced by the presence of co-factors such as elongation factor 1α (EF-1α), polypyrimidine tract-binding protein (PTB), and the chaperonin-like protein stimulator of TAR RNA-binding proteins (SRB). TRBP1 may act to disengage RNA polymerase II from TAR during transcriptional elongation if the RNA polymerase stalls at the TAR during transcriptional elongation.

Immunogen

TRBP1 antibody was raised against a 17 amino acid synthetic peptide from near the center of human TRBP1.The immunogen is located within amino acids 1310 - 1360 of TRBP1.

Application

TRBP1 antibody can be used for detection of TRBP1 by Western blot at 1 - 2 μg/mL. Antibody validated: Western Blot in mouse samples. All other applications and species not yet tested.

Physical form

Supplied in PBS containing 0.02% sodium azide.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: nwg
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable