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Key Documents

SAB1302862

Sigma-Aldrich

ANTI-DLL3 (C-TERM) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

Synonym(s):

DLL3, Delta-like protein 3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41
conjugate:
unconjugated
application:
IHC
WB
clone:
polyclonal
species reactivity:
human
citations:
2
technique(s):
immunohistochemistry: 1:50-1:100
western blot: 1:250-1:500

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

64618 Da

species reactivity

human

technique(s)

immunohistochemistry: 1:50-1:100
western blot: 1:250-1:500

NCBI accession no.

NP_058637.1

UniProt accession no.

Q9NYJ7

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... DLL3(10683)

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
SA100423AI
SA110402BI

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Christiane Kuempers et al.
Frontiers in medicine, 8, 734901-734901 (2021-10-26)
Rovalpituzumab tesirine (Rova-T), an antibody-drug conjugate directed against Delta-like protein 3 (DLL3), is under development for patients with small cell lung cancer (SCLC). DLL3 is expressed on the majority of SCLC samples. Because SCLC is rarely biopsied in the course
Orgilmaa Regzedmaa et al.
OncoTargets and therapy, 12, 10043-10055 (2019-12-11)
Immune-based and antibody-drug conjugate therapies have shown promise in the treatment of patients with small cell lung cancer (SCLC). However, better predictive biomarkers are needed for selection of the appropriate SCLC patients for these advanced therapies and also for evaluation

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