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N9161

Sigma-Aldrich

Notch-2/Fc Chimera from rat

recombinant, expressed in NSO cells, ≥90% (SDS-PAGE), lyophilized powder

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About This Item

MDL number:
MFCD06412282
UNSPSC Code:
12352202
NACRES:
NA.26

biological source

rat

Quality Level

200

recombinant

expressed in NSO cells

Assay

≥90% (SDS-PAGE)

form

lyophilized powder

mol wt

105-115 kDa by SDS-PAGE (reducing)
calculated mol wt 76.5 kDa

impurities

endotoxin, tested

UniProt accession no.

Q9QW30

application(s)

cell analysis

storage temp.

−20°C

Gene Information

rat ... Notch2(29492)

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Analysis Note

The biological activity is measured by its ability to bind Jagged-1.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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G Weinmaster et al.
Development (Cambridge, England), 116(4), 931-941 (1992-12-01)
Notch is a cell surface receptor that mediates a wide variety of cellular interactions that specify cell fate during Drosophila development. Recently, homologs of Drosophila Notch have been isolated from Xenopus, human and rat, and the expression patterns of these
G Weinmaster
Current opinion in genetics & development, 10(4), 363-369 (2000-07-13)
The Notch signaling pathway functions in a wide variety of processes that regulate tissue patterning and morphogenesis in developing vertebrates and invertebrates. Research on the mechanism of ligand-induced Notch signal transduction has revealed a novel and essential element in the

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