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M005

S-(+)-Deprenyl hydrochloride

solid

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About This Item

Empirical Formula (Hill Notation):
C13H17N · HCl
CAS Number:
4528-52-3
Molecular Weight:
223.74
UNSPSC Code:
12352200
PubChem Substance ID:
24896532
MDL number:
MFCD00069300
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form

solid

optical activity

[α]24/D +11.84°, c = 0.1 in H2O(lit.)

color

white

solubility

H2O: soluble

SMILES string

Cl.C[C@@H](Cc1ccccc1)N(C)CC#C

Biochem/physiol Actions

Less active enantiomer of deprenyl.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificates of Analysis (COA)

Lot/Batch Number
011K4600

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R E Heikkila et al.
Nature, 311(5985), 467-469 (1984-10-04)
1-Methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP) causes degeneration of the dopaminergic nigrostriatal pathway in several animal species, including humans, monkeys and mice. Changes observed after MPTP administration include marked decrements in the neostriatal content of dopamine and its major metabolites, dihydroxyphenylacetic acid and homovanillic
Dhaval R Kalaria et al.
International journal of pharmaceutics, 438(1-2), 202-208 (2012-09-08)
The objective was to investigate the anodal iontophoresis of the MAO-B inhibitors rasagiline (RAS) and selegiline (SEL) across porcine and human skin in vitro. Passive delivery of RAS and SEL from aqueous solution was minimal; however, increasing current density from
Jorge A Zavala et al.
Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, 19(9), 1298-1299 (2012-06-23)
Pramipexole is a non-ergot dopamine agonist that is used frequently as a single therapy or in combination for the management of Parkinson's disease. Common side effects are daytime drowsiness, hypotension, hallucinations and compulsive behaviour. We describe a patient who developed
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