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GE17371502

Capto Adhere ImpRes, 100 ML

Cytiva 17371502, 40 μm avg. part. size (median particle size of the cumulative volume distribution)

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About This Item

UNSPSC Code:
47101511
NACRES:
NA.56

ligand

(Multimodal strong anion exchanger)

manufacturer/tradename

Cytiva 17371502

matrix

high-flow agarose

avg. part. size

40 μm (median particle size of the cumulative volume distribution)

cleaning in place

2-14

working range

3-12

capacity

45-85 mg Mab/ml binding capacity

General description

The multimodal anion exchanger ligand of Capto adhere ImpRes is immobilized to the base matrix and interacts with the target molecule through multiple types of interactions.

The high selectivity of the anion multimodal ligand allows operation in a variety of process conditions to solve challenging purification problems. Contaminants such as DNA, host cell proteins, leached protein A, aggregates, and viruses are efficiently removed.

Capto adhere ImpRes is available in a range of different bulk pack sizes for easy scale-up and pre-packed formats for process development.

As member of the BioProcess media range, Capto adhere ImpRes meets industrial demands with security of supply and comprehensive technical and regulatory support.

Features and Benefits

Capto adhere ImpRes is a strong anion exchange multimodal BioProcess chromatography medium (resin), designed to meet the demands of modern large-scale manufacturers, for high-resolution polishing of monoclonal antibodies (MAbs) and other biomolecules.

  • High yields achieved through the high-resolution beads and selectivity of the ligand.
  • Efficient removal of aggregates, viruses, and main contaminants in MAb processes.
  • Enables use of a platform approach to MAb process development.
  • Allows separation of MAb charged variants.

Storage and Stability

Store at 4 to 30 °C (20% ethanol)

Analysis Note

To view the Certificate of Analysis for this product, please visit www.cytiva.com.

Pictograms

Flame
GHS02

Signal Word

Warning

Hazard Statements

H226

Storage Class Code

3 - Flammable liquids

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Articles

Polishing of MAbs Using Capto Adhere ImpRes in Bind/Elute Mode

In these studies, the binding capacity for MAbs and the efficiency in the clearance of impurities using Capto adhere ImpRes in bind/elute mode was evaluated.

Maintenance of Multimodal Chromatography Media and Storage Conditions

This page describes the maintenance of media and storage conditions for multimodal chromatography using Cytiva products.

Protocols

Capto Adhere ImpRes

Capto adhere ImpRes is a cost-effective and flexible chromatography medium from Cytiva, designed for high-resolution polishing of MAbs.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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