F8190
Fucoidan from Fucus vesiculosus
≥95%
Synonym(s):
Fucoidin
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About This Item
Recommended Products
biological source
algae (Fucus Vesiculosus)
Assay
≥95%
form
powder
color
light yellow
useful pH range
5.0-11.0
solubility
water: 10 mg/mL, clear, colorless to faintly yellow
storage temp.
room temp
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General description
Fucoidan is a fucose-rich, sulfated polysaccharide isolated from several species of brown seaweed.
Application
Fucoidan from Fucus vesiculosus has been to:
- study the application of heparin red in detecting fucoidan
- study its bioactivity as an antimicrobial agent
- study its effects on advanced glycation end-products
Biochem/physiol Actions
Studies of fucoidan have found it to have a broad variety of biological activities including antitumor and antiangogenic activities, immunomodulatory, anti-inflammatory, anticoagulant, antithrombotic, and antioxidant activities. Fucoidan induces macrophage activation with subsequently activates mitogen activated protein kinases (MAPKs) and results in natural killer cell proliferation. Fucoidan acts as a nonselective selectin blocker and has been shown to induce apoptosis and suppress angiogenesis.
Other Notes
To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Certificates of Analysis (COA)
Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.
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Effects of scavenger receptors-1 class A stimulation on macrophage morphology and highly modified advanced glycation end product-protein phagocytosis
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Poveda-Castillo et al.
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Fanlu Wang et al.
Marine drugs, 19(4) (2021-04-04)
Fucoidans, sulfated polysaccharides extracted from brown algae, are marine products with the potential to modulate bone formation and vascularization processes. The bioactivity and safety of fucoidans are highly associated with their chemical structure, which may vary with algae species and
Li-Mei Chen et al.
Scientific reports, 7(1), 11864-11864 (2017-09-21)
Low-molecular-weight Fucoidan (Oligo-Fucoidan) is a sulfated polysaccharide that has a variety of biological effects and has also been shown to have beneficial health effects. However, the molecular mechanisms underlying the therapeutic effects of Oligo-Fucoidan in patients with cancer remain unclear.
Jie Zhang et al.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 130, 110534-110534 (2020-07-28)
Doxorubicin (DOX) is well-known for its potent antitumor activity but limited by its multiple and serious adverse effects. A major adverse effect is acute cardiotoxicity; yet, its mechanism has not been elucidated. Fucoidan is a multifunctional and nontoxic polysaccharide that
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