D6035

Disopyramide phosphate salt

• Synonym(s): α-Diisopropylaminoethyl-α-phenylpyridine-2-acetamide
• Linear Formula: C₂₁H₂₉N₃O · H₃PO₄
• CAS Number: 22059-60-5
• Molecular Weight: 437.47
• EC Number: 244-756-1
• MDL number: MFCD00069254
• UNSPSC Code: 12352200
• PubChem Substance ID: 24277706
• NACRES: NA.77

Properties

• form: solid
• SMILES string: OP(O)(O)=O.CC(C)N(CCC(C(N)=O)(c1ccccc1)c2ccccn2)C(C)C
• InChI: 1S/C21H29N3O.H3O4P/c1-16(2)24(17(3)4)15-13-21(20(22)25,18-10-6-5-7-11-18)19-12-8-9-14-23-19;1-5(2,3)4/h5-12,14,16-17H,13,15H2,1-4H3,(H2,22,25);(H3,1,2,3,4)
• InChI key: CGDDQFMPGMYYQP-UHFFFAOYSA-N
• Gene Information: human ... SCN10A(6336) , SCN11A(11280) , SCN1A(6323) , SCN2A(6326) , SCN3A(6328) , SCN4A(6329) , SCN5A(6331) , SCN7A(6332) , SCN8A(6334) , SCN9A(6335)

Description

Application

Disopyramide phosphate salt has been used as an internal standard for plasma sample analysis by mass spectrometry. It might be used as a test compound in a teratogenicity study.

Biochem/physiol Actions

Disopyramide is found to stabilize the cell membrane by altering the action potential. It might act as an antiarrhythmic agent.

Class IA antiarrhythmic; sodium channel blocker

Safety Information

• Pictograms: GHS07
• Signal Word: Warning
• Hazard Statements: H302
• Precautionary Statements: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves