C9504
Coenzyme Q6
Synonym(s):
2,3-Dimethoxy-5-methyl-6-(farnesylfarnesyl)-1,4-benzoquinone, Ubiquinone-30
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About This Item
Empirical Formula (Hill Notation):
C39H58O4
CAS Number:
Molecular Weight:
590.88
MDL number:
UNSPSC Code:
12352204
PubChem Substance ID:
Recommended Products
biological source
Saccharomyces cerevisiae
storage temp.
−20°C
SMILES string
COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(\C)C)=C(C)C1=O
Packaging
Sealed ampule.
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Coq3 and Coq4 define a polypeptide complex in yeast mitochondria for the biosynthesis of coenzyme Q.
Beth Marbois et al.
The Journal of biological chemistry, 280(21), 20231-20238 (2005-03-29)
Coenzyme Q (Q) is a redox active lipid essential for aerobic respiration in eukaryotes. In Saccharomyces cerevisiae at least eight mitochondrial polypeptides, designated Coq1-Coq8, are required for Q biosynthesis. Here we present physical evidence for a coenzyme Q-biosynthetic polypeptide complex
Mohammad Ozeir et al.
Chemistry & biology, 18(9), 1134-1142 (2011-09-29)
Coenzyme Q (Q), an essential component of eukaryotic cells, is synthesized by several enzymes from the precursor 4-hydroxybenzoic acid. Mutations in six of the Q biosynthesis genes cause diseases that can sometimes be ameliorated by oral Q supplementation. We establish here
Daniel J M Fernández-Ayala et al.
Biochimica et biophysica acta, 1706(1-2), 174-183 (2004-12-29)
Coenzyme Q (Q) is an obligatory component of both respiratory chain and uncoupling proteins. Also, Q acts as an antioxidant in cellular membranes. Several neurodegenerative diseases are associated with modifications of Q10 levels. For these reasons, therapies based on Q
Mario H Barros et al.
The Journal of biological chemistry, 280(52), 42627-42635 (2005-10-19)
Deletion of the Saccharomyces cerevisiae gene YOL008W, here referred to as COQ10, elicits a respiratory defect as a result of the inability of the mutant to oxidize NADH and succinate. Both activities are restored by exogenous coenzyme Q2. Respiration is
Sergio Padilla-López et al.
Biochimica et biophysica acta, 1788(6), 1238-1248 (2009-04-07)
Coenzyme Q is an isoprenylated benzoquinone lipid that functions in respiratory electron transport and as a lipid antioxidant. Dietary supplementation with Q is increasingly used as a therapeutic for treatment of mitochondrial and neurodegenerative diseases, yet little is known regarding
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