AC-0336

CD42b (EP409) Rabbit Monoclonal Primary Antibody

• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 500
• antibody form: Ig fraction of antiserum
• clone: monoclonal
• description: For In Vitro Diagnostic Use in Select Regions (See Chart)
• form: buffered aqueous solution
• technique(s): immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:200
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: (membrane/cytoplasm)

Description

General description

CD42b, encoded by the GP1BA gene, is a surface membrane glycoprotein expressed on the membrane of megakaryocytes, splenocytes and platelets. CD42b forms a part of the CD42a-d complex (also called the glycoprotein Ib-IX-V receptor) and is the surface platelet receptor for von Willebrand factor (vWF) on endothelium. CD42b is useful in differentiating acute megakaryoblastic leukemia subtype M7 (AML-M7) that are typically positive for CD41, CD42b and CD61 from acute myelofibrosis, which are CD42b negative.

Quality

IVD

IVD

IVD

RUO

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and &< 0.1% Sodium Azide

Other Notes

For a copy of the IFU and CofA contact [email protected]

For Technical Service please contact: 800-665-7284 or email: [email protected]

Safety Information

• Storage Class Code: 10 - Combustible liquids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable