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A3097

Sigma-Aldrich

[Pro18, Asp21]-Amyloid β Protein Fragment 17-21 trifluoroacetate salt

≥98% (HPLC), solid

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About This Item

Empirical Formula (Hill Notation):
C33H43N5O8
CAS Number:
182912-74-9
Molecular Weight:
637.72
MDL number:
MFCD01862668
UNSPSC Code:
12352200

Assay

≥98% (HPLC)

form

solid

UniProt accession no.

P05067

storage temp.

−20°C

SMILES string

CC(C)C[C@H](N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CC(O)=O)C(O)=O

Gene Information

human ... APP(351)

Amino Acid Sequence

Leu-Pro-Phe-Phe-Asp

Biochem/physiol Actions

Inhibits amyloid formation in vitro, prevents amyloid neurotoxicity in cell culture, reduces in vivo cerebral amyloid deposition and completely blocks amyloid fibrial formation in rat brain.

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