ADORA2A is an adenosine receptor and part of the G-protein coupled receptor family of proteins. ADORA2A is involved in regulating myocardial blood flow and dopamine release in the brain.
Anti-A2A Adenosine Receptor is specific for A2A adenosine receptor adenosine receptor subtype. By immunoblotting, it reacts strongly with canine A2A. However, it does not react with rat A2A. The antibody detects A2A adenosine receptor in human hippocampus by immunohistology and may be used for immunoprecipitation.
Immunogen
Synthetic peptide (Ser-His-Gly-Asp-Met-Gly-Leu-Pro-Asp-Val-Glu-Leu-Leu-Ser-His-Glu-Leu-Lys) derived from amino acids 373-391 of the canine A2A adenosine receptor C-terminal domain.
Application
Rabbit anti-A2A adenosine receptor antibody can be used for western blot applications. The antibody can also be used for immunohistochemistry (1:100, frozen sections) and immunoprecipitation applications.
Physical form
Solution in phosphate buffered saline, containing 1 mg/ml BSA and 0.05% sodium azide.
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Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
The Journal of pharmacology and experimental therapeutics, 305(2), 581-586 (2003-02-28)
Hypertension in spontaneously hypertensive rats (SHRs) is due in part to enhanced effects of vasoactive peptides on the renal vasculature. We hypothesize that the G(i) signal transduction pathway enhances renovascular responses to vasoactive peptides in SHRs more so than in
Adenosine receptor (ADOR) antagonists, such as 7-methylxanthine (7-MX), have been shown to slow myopia progression in humans and animal models. Adenosine receptors are found throughout the body, and regulate the release of neurotransmitters such as dopamine and glutamate. However, the
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