88559
2,2′-Thiodiethanol
≥99.0% (GC)
Synonym(s):
2,2′-Thiobis(ethanol), Bis(2-hydroxyethyl) sulfide, Thiodiethylene glycol, Thiodiglycol
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About This Item
Linear Formula:
S(CH2CH2OH)2
CAS Number:
Molecular Weight:
122.19
Beilstein:
1236325
EC Number:
MDL number:
UNSPSC Code:
12352200
PubChem Substance ID:
Recommended Products
Assay
≥99.0% (GC)
refractive index
n20/D 1.521
n20/D 1.5215 (lit.)
bp
164-166 °C/20 mmHg (lit.)
mp
−16 °C (lit.)
density
1.221 g/mL at 25 °C (lit.)
SMILES string
OCCSCCO
InChI
1S/C4H10O2S/c5-1-3-7-4-2-6/h5-6H,1-4H2
InChI key
YODZTKMDCQEPHD-UHFFFAOYSA-N
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Application
Thiodiglycol (2,2′-Thiodiethanol, TDE) is used as a solvent and as a refractive index modifying component of mounting media for microscopy. Thiodiglycol may also be used as a charge modifier for procedures such as electrospray ionization mass spectrometry. Thiodiglycol is used as a reference material in the evaluation of the degradation of sulfur mustard gas by bacteria.
Other Notes
This product has been replaced by 166782-ALDRICH | 2,2′-Thiodiethanol ≥99%
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 1
Flash Point(F)
235.4 °F - closed cup
Flash Point(C)
113 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Journal of hazardous materials, 167(1-3), 124-127 (2009-01-31)
Microbial degradation of thiodiglycol (bis(2-hydroxyethyl)sulfide, TDG) with petroleum-desulfurizing soil bacteria was examined. Among the bacteria tested, several strains belonging to the genera Rhodococcus and Gordonia grew on TDG as the sole sulfur source. The selected strain Rhodococcus sp. strain T09
G Karvaly et al.
Journal of applied toxicology : JAT, 28(1), 21-26 (2007-04-13)
Subcutaneous microdialysis was employed for monitoring thiodiglycol (2,2'-thiodiethanol, TDG) levels with the aim of characterizing the transdermal penetration of topically applied liquid sulfur mustard (2,2'-dichlorodiethyl sulfide, SM) in rats. TDG levels, evaluated in 20 min dialysates collected over a 6
Hong Li et al.
Biodegradation, 24(1), 125-135 (2012-07-04)
Thiodiglycol (TDG) is both the precursor for chemical synthesis of mustard gas and the product of mustard gas hydrolysis. TDG can also react with intermediates of mustard gas degradation to form more toxic and/or persistent aggregates, or reverse the pathway
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