137263
Tromethamine
EMPROVE® EVOLVE
Pharma Manufacturing
Synonym(s):
Tromethamine, Tris
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About This Item
Empirical Formula (Hill Notation):
C4H11NO3
CAS Number:
Molecular Weight:
121.14
MDL number:
UNSPSC Code:
12352116
Recommended Products
biological source
synthetic
Quality Level
product line
EMPROVE® EVOLVE
form
powder
technique(s)
cell culture | mammalian: suitable
impurities
Endotoxin, microbial, and trace metals, tested
suitability
suitable for manufacturing use
storage temp.
2-30°C
SMILES string
NC(CO)(CO)CO
InChI
1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2
InChI key
LENZDBCJOHFCAS-UHFFFAOYSA-N
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Application
Tromethamine is a commonly used biological buffer which is also referred to as Tris or Trizma. Tris as a buffer has very broad usage in diagnostics and downstream purifications. The pKa of Tris is 7.77 which corresponds closely to a physiological pH of 7.36.Tromethamine is used in biopharmaceutical buffer formulations (both upstream and downstream), electrophoresis separations and diagnostic reagent formulations. Tromethamine is especially useful in downstream purification processes.
Legal Information
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
Storage Class Code
11 - Combustible Solids
WGK
WGK 1
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
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