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T6159

Supelco

Trimebutine

analytical standard

Synonym(s):

3,4,5-Trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutyl ester

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About This Item

Empirical Formula (Hill Notation):
C22H29NO5
CAS Number:
39133-31-8
Molecular Weight:
387.47
EC Number:
254-309-2
MDL number:
MFCD00133873
UNSPSC Code:
41116107
PubChem Substance ID:
329826841
NACRES:
NA.24
Pricing and availability is not currently available.

grade

analytical standard

Quality Level

200

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

storage temp.

2-8°C

SMILES string

CCC(COC(=O)c1cc(OC)c(OC)c(OC)c1)(N(C)C)c2ccccc2

InChI

1S/C22H29NO5/c1-7-22(23(2)3,17-11-9-8-10-12-17)15-28-21(24)16-13-18(25-4)20(27-6)19(14-16)26-5/h8-14H,7,15H2,1-6H3

InChI key

LORDFXWUHHSAQU-UHFFFAOYSA-N

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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M Delvaux et al.
The Journal of international medical research, 25(5), 225-246 (1997-11-19)
The actions of trimebutine [3,4,5-trimethoxybenzoic acid 2-(dimethylamino)-2-phenylbutylester] on the gastrointestinal tract are mediated via (i) an agonist effect on peripheral mu, kappa and delta opiate receptors and (ii) release of gastrointestinal peptides such as motilin and modulation of the release
Véronique Vitton et al.
World journal of gastroenterology, 18(14), 1610-1615 (2012-04-25)
To report the results of a medical management of sphincter of oddi dysfunction (SOD) after an intermediate follow-up period. A total of 59 patients with SOD (2 men and 57 women, mean age 51 years old) were included in this
Shiho Okano et al.
Journal of pharmacological sciences, 98(4), 411-418 (2005-08-05)
Stress-induced colonic functional changes have been investigated mainly under conditions involving physical stress, like in the restraint stress model. In this study, we established a new stress-induced defecation model involving the placement of Mongolian gerbils in a novel environment (novelty
Wei Tan et al.
Archives of pharmacal research, 34(6), 979-985 (2011-07-05)
The effects of trimebutine maleate (TM) on spontaneous contractions of colonic longitudinal muscle were investigated in guinea pigs. The contractile responses of smooth muscle strips were recorded by an isometric force transducer. Membrane and action potentials were detected by an
Sun-Hee Lee et al.
Archives of pharmacal research, 35(9), 1599-1607 (2012-10-12)
This study showed near Infrared (NIR) and Raman spectroscopy with a multivariate calibration approach were very effective to determine blend uniformity end-point. A set of 36 trimebutine samples containing magnesium stearate, stearic acid, colloidal silicon oxide, talc as excipients (0.9%∼1.8%)
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