Skip to Content
Merck
All Photos(1)

Key Documents

View All Documentation

B0760

Supelco

Bufexamac

analytical standard

Synonym(s):

2-(p-Butoxyphenyl)acetohydroxamic acid

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C12H17NO3
CAS Number:
2438-72-4
Molecular Weight:
223.27
EC Number:
219-451-1
MDL number:
MFCD00078936
UNSPSC Code:
41116107
PubChem Substance ID:
329773128
NACRES:
NA.24

grade

analytical standard

Quality Level

100

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

format

neat

SMILES string

CCCCOc1ccc(CC(=O)NO)cc1

InChI

1S/C12H17NO3/c1-2-3-8-16-11-6-4-10(5-7-11)9-12(14)13-15/h4-7,15H,2-3,8-9H2,1H3,(H,13,14)

InChI key

MXJWRABVEGLYDG-UHFFFAOYSA-N

Looking for similar products? Visit Product Comparison Guide

General description

Bufexamac is a drug with antipyretic, analgesic and anti-inflammatory properties.

Application

Bufexamac may be used as a reference standard in the determination of bufexamac in pharmaceutical formulations using high-performance liquid chromatography (HPLC).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Recommended products

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Storage Class Code

11 - Combustible Solids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number
BCBW0026
011M1532V
011M1532

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Allergic contact dermatitis with spreading over extensive regions due to topical use of 5% bufexamac ointment.
Junko Arikawa et al.
The Journal of dermatology, 31(2), 136-138 (2004-05-27)
Yoshiki Seto et al.
Journal of pharmaceutical and biomedical analysis, 55(3), 591-596 (2011-03-25)
The present study aimed to modulate the photoreactivity of bufexamac, with a focus on photostability and phototoxicity, by forming an inclusion complex with sulfobutylether-β-cyclodextrin (SBECD). The photobiochemical properties of bufexamac were evaluated by reactive oxygen species (ROS) assay and using
Yan Pan et al.
The Australasian journal of dermatology, 53(3), 207-210 (2012-08-14)
In Australia bufexamac is mainly used for pharmacist-initiated local treatment of various dermatoses. The European Medicines Agency's Committee for Medicinal Products for Human Use recently recommended that marketing authorisation for bufexamac-containing preparations be revoked throughout the European Union because of
P H Marttinen et al.
Journal of veterinary medicine. A, Physiology, pathology, clinical medicine, 53(6), 311-318 (2006-08-12)
The objective here was to evaluate the acute effects of induced arthritis on synovial fluid (SF) levels of matrix metalloproteinases (MMP) -2, -8 and -9 in horses. To evaluate MMP-2 and -9 activities and the effect of non-steroidal anti-inflammatory drug
Katrin Kügler et al.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG, 3(12), 979-986 (2006-01-13)
Anogenital dermatoses (AGD) are common and often very distressing. Clinically it is often unclear if allergic contact dermatitis or irritant dermatitis is involved. In order to optimize therapy and prophylaxis, it is essential to identify relevant allergens or irritants. Data
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service