The Annals of pharmacotherapy, 30(9), 935-940 (1996-09-01)
To compare the rate and extent of systemic salicylate absorption following single and multiple applications of two topically applied analgesics, one containing methyl salicylate and the other containing trolamine salicylate. Two-period, two-treatment, randomized, crossover, multiple-dose study in healthy men and
Recently, triethanolamine salicylate (TEAS) is frequently being incorporated in several over-the-counter topical analgesic pharmaceutical products. Since the clinical efficacy of such dosage form depends upon the release of the active ingredient at the site of application, the present study was
The purpose of this study was to determine the effects of ultrasound and phonophoresis using an anti-inflammatory-analgesic cream (trolamine salicylate) on delayed-onset muscle soreness (DOMS). Repeated eccentric contractions were used to induce DOMS in the elbow flexors of 40 college-aged
Journal of clinical pharmacology, 24(11-12), 532-539 (1984-11-01)
The transdermal absorption by tissues of salicylate from triethanolamine salicylate (TEA/S) ointment applied to canine and human skin was shown to be consistent, significant, and reproducible. Salicylate levels were measured using thin-layer chromatography, nuclear magnetic resonance, and radiochemistry. Absorption was
Medicine and science in sports and exercise, 23(4), 397-401 (1991-04-01)
The purpose of this investigation was to determine the effect of ultrasound intensity and mode on serum salicylate levels following phonophoresis. Approximately 12-13 g of a salicylate product (Myoflex) was applied to the right anterior forearm of five males and
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