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292664

Sigma-Aldrich

N-tert-Butyl-α-(2-sulfophenyl)nitrone sodium salt

95%

Synonym(s):

2-SPBN sodium salt, 2-Sulfonatophenyl tert-butyl nitrone sodium salt

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About This Item

Linear Formula:
NaO3SC6H4CH=N(O)C(CH3)3
CAS Number:
73475-11-3
Molecular Weight:
279.29
MDL number:
MFCD00012017
UNSPSC Code:
12171500
PubChem Substance ID:
24857605
NACRES:
NA.47
Pricing and availability is not currently available.

Assay

95%

form

powder or crystals

mp

246 °C (dec.) (lit.)

application(s)

diagnostic assay manufacturing
hematology
histology

storage temp.

room temp

SMILES string

[Na+].CC(C)(C)[N+](\[O-])=C\c1ccccc1S([O-])(=O)=O

InChI

1S/C11H15NO4S.Na/c1-11(2,3)12(13)8-9-6-4-5-7-10(9)17(14,15)16;/h4-8H,1-3H3,(H,14,15,16);/q;+1/p-1/b12-8-;

InChI key

LAIQBHGUFDAJKL-JCTPKUEWSA-M

Application

Water-soluble, negatively-charged spin trap used to monitor aqueous phase of SDS micelles.[1]

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
10807DJ
21323LD
15211CZ
13513CQ
13427KR

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Catherine E Hobbs et al.
Pediatrics international : official journal of the Japan Pediatric Society, 50(4), 481-488 (2008-10-22)
The production of oxygen free radicals after perinatal hypoxia-ischemia is thought to play a critical role in the pathogenesis of the brain injury. Administration of anti-oxidants may thus be neuroprotective. The aim of the present study was to investigate the
Maria Molnar et al.
Upsala journal of medical sciences, 115(3), 163-168 (2010-07-20)
Hyperglycemia exacerbates focal ischemic brain damage supposedly through various mechanisms. One such mechanism is oxidative stress involving reactive oxygen and nitrogen species (RONS) production. Nitrones attenuate oxidative stress in various models of brain injury. Sodium 2-sulfophenyl-N-tert-butyl nitrone (S-PBN) can be
Caroline Gahm et al.
Neurosurgery, 57(6), 1272-1281 (2005-12-07)
Nitric oxide (NO) and oxygen free radicals are implicated in the pathophysiology of traumatic brain injury (TBI). Peroxynitrite formation from NO and superoxide contributes to secondary neuronal injury but the neuroprotective effects of nitric oxide synthase (NOS)-inhibitors have been contradictory.
Journal of the American Chemical Society, 106, 1962-1962 (1984)
Steven L Peterson et al.
Neurotoxicology, 26(6), 969-979 (2005-05-14)
The status epilepticus (SE) induced in rats by lithium-pilocarpine (Li-pilo) shares many common features with soman-induced SE including extensive limbic neuropathology. Reactive oxygen species are hypothesized to play a role in the SE induced neuropathology and we propose that the
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