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Key Documents

00583

Sigma-Aldrich

Nitrous oxide

≥99.998%

Synonym(s):

Dinitrogen monoxide, Laughing gas

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About This Item

Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
Beilstein:
8137358
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22

vapor density

1.53 (15 °C, vs air)

vapor pressure

51.7 mmHg ( 21 °C)

Assay

≥99.998%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

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Application

Nitrous oxide can be used as:
  • A nitrogen donor to synthesize alkynyl and alkenyl substituted triazenes by coupling reaction with lithium amides and organomagnesium compounds.
  • A reagent to synthesize azoimidazolium dyes.

N2O can also be reacted with N-heterocyclic olefins (NHOs) to form electron-rich azo-bridged NHO dimers.

Packaging

pressure tin
filling pressure at 15°C: 11 bar; content (15°C, 1 bar): 11 l

Other Notes

Sales restrictions may apply

Signal Word

Danger

Hazard Statements

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

2A - Gases

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of azoimidazolium dyes with nitrous oxide
Tskhovrebov AG, et al.
Angewandte Chemie (International Edition in English), 127, 1305-1308 (2015)
Synthesis of triazenes with nitrous oxide
Kiefer G, et al.
Angewandte Chemie (International Edition in English), 54, 302-305 (2015)
Synthesis of organic super-electron-donors by reaction of nitrous oxide with n-heterocyclic olefins
Eymann LYM, et al.
Journal of the American Chemical Society, 141, 17112-17116 (2019)
R L M Schils et al.
Animal : an international journal of animal bioscience, 7 Suppl 1, 29-40 (2012-10-04)
Herbivores are a significant source of nitrous oxide (N(2)O) emissions. They account for a large share of manure-related N(2)O emissions, as well as soil-related N(2)O emissions through the use of grazing land, and land for feed and forage production. It
Roberta Corona et al.
Fertility and sterility, 100(6), 1777-1783 (2013-10-12)
To evaluate the effect of addition of nitrous oxide (N2O) to the carbon dioxide (CO2) pneumoperitoneum (PP) and the effect of blood, plasma, or red blood cells (RBCs) on postoperative adhesions in a laparoscopic mouse model. Prospective randomized controlled trial.

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